Bromhexine Hydrochloride Tablets for the Treatment of Moderate COVID‐19: An Open‐Label Randomized Controlled Pilot Study [PDF]
Clinical and Translational Science, Volume 13, Issue 6, Page 1096-1102, November 2020., 2020 This open‐label randomized controlled pilot study aimed to test the study feasibility of bromhexine hydrochloride (BRH) tablets for the treatment of mild or moderate coronavirus disease 2019 (COVID‐19) and to explore its clinical efficacy and safety. Patients with mild or moderate COVID‐19 were randomly divided into the BRH group or the control group ...
Ting Li +9 more
wiley +2 more sources
Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride to control SARS-coronavirus-2: A molecular modeling approach [PDF]
Informatics in Medicine Unlocked, 2021 Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been responsible for the cause of global pandemic Covid-19 and to date, there is no effective treatment available.
Kailas D. Sonawane +11 more
doaj +2 more sources
Investigating the Impact of Co-processed Excipients on the Formulation of Bromhexine Hydrochloride Orally Disintegrating Tablets (ODTs) [PDF]
Pharmaceutical Research, 2023 Abstract Purpose Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in pharmacotherapy for over 20 years since they overcome the problems with swallowing solid dosage forms. The successful formula manufactured by direct compression shall ensure acceptable mechanical strength and short ...
Krzysztof Woyna-Orlewicz +11 more
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Bromhexine inhibits SARS-CoV-2 Omicron and variant pseudovirus infection via ACE2-targeted mechanisms [PDF]
Frontiers in PharmacologyBackgroundSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes a highly infectious disease characterized by fever, acute respiratory illness, and pneumonia, known as coronavirus disease 2019 (COVID‐19).
Rafael Zúñiga +11 more
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Bromhexine hydrochloride enhances the therapeutic efficacy of tiamulin against experimental Staphylococcus aureus infection in dogs: targeting bacterial virulence, boosting antioxidant defense, and improving histopathology [PDF]
Frontiers in PharmacologyIntroductionStaphylococcus aureus is a prominent pathogen capable of causing systemic infections and multi-organ damage, primarily driven by its high virulence and induction of oxidative stress.
Hanem F. El-Gendy +8 more
doaj +2 more sources
An electrochemical sensor based on poly(procaterol hydrochloride)/carboxyl multi-walled carbon nanotube for the determination of bromhexine hydrochloride [PDF]
RSC Advances, 2019 The fabrication process of the p-ProH/CMWCNT/GCE.
Dexian Kong +8 more
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Effect of increasing doses of colchicine on the treatment of 333 COVID‐19 inpatients [PDF]
Immunity, Inflammation and Disease, Volume 12, Issue 5, May 2024.We present 333 cases treated with increased doses of colchicine, provided by different hospital centers. The result clearly shows that at higher, nonlife‐threatening doses of colchicine, the mortality rate drops sharply. Abstract Background Previous research done in Bulgaria demonstrated a fivefold reduction in mortality from COVID‐19 with increased ...
Rumen Tiholov +5 more
wiley +2 more sources
Pancreatic Pseudocyst With Thoracic Extension: A Clinicoradiological Case Report [PDF]
Clinical Case Reports, Volume 14, Issue 1, January 2026.CECT sagittal view shows an enlarged, heterogeneously enhancing pancreas with a peripancreatic collection extending into the posterior mediastinum and compressing the esophagus with massive right pleural fluid noted. ABSTRACT Pancreatic pseudocysts are encapsulated, enzyme‐rich peripancreatic fluid collections that typically develop following acute or ...
Sachchu Thapa +7 more
wiley +2 more sources
Development of a rapid method for the simultaneous determination of aminophylline, doxofylline, bromhexine, and ambroxol by HPLC [PDF]
Science ProgressIntroduction: Antitussive and expectorant drugs such as aminophylline (APL), doxofylline (DXL), bromhexine hydrochloride (BXH), and ambroxol hydrochloride (AXH), either individually or in combination, are widely used in the prevention and treatment of ...
Xia Meng +4 more
doaj +2 more sources
Comparative Pharmacokinetics and Egg Residues of Amoxicillin, Single and in Combination with Bromhexine, in Laying Hens [PDF]
PathogensThe need for antibiotics in commercial laying hens is increasing owing to intensive farming systems. Amoxicillin trihydrate (AMX), an aminopenicillin β-lactam antibiotic, exerts broad bactericidal activity.
Jeong-Won Kim +8 more
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