Bromhexine inhibits SARS-CoV-2 Omicron and variant pseudovirus infection via ACE2-targeted mechanisms [PDF]
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes a highly infectious disease characterized by fever, acute respiratory illness, and pneumonia, known as coronavirus disease 2019 (COVID‐19).
Rafael Zúñiga +11 more
doaj +2 more sources
Pilot survey among patients taking bromhexine prophylactically against influenza [PDF]
Background: The successful use of bromhexine hydrochloride (BRH) for COVID-19 prevention led us to apply the same method for flu prevention. The goal of this study is to observe whether BRH could protect people against influenza.
Vanyo Mitev +11 more
doaj +2 more sources
An electrochemical sensor based on poly(procaterol hydrochloride)/carboxyl multi-walled carbon nanotube for the determination of bromhexine hydrochloride. [PDF]
The fabrication process of the p-ProH/CMWCNT/GCE.
Kong D +8 more
europepmc +4 more sources
Bromhexine hydrochloride enhances the therapeutic efficacy of tiamulin against experimental Staphylococcus aureus infection in dogs: targeting bacterial virulence, boosting antioxidant defense, and improving histopathology [PDF]
IntroductionStaphylococcus aureus is a prominent pathogen capable of causing systemic infections and multi-organ damage, primarily driven by its high virulence and induction of oxidative stress.
Hanem F. El-Gendy +8 more
doaj +2 more sources
In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride
ABSTRACT The world is enduring the SARS CoV-2 pandemic, and although extensive research has been conducted on the issue, only a few antivirals have been approved to treat patients with COVID-19. Bromhexine hydrochloride was previously identified as a potent inhibitor of TMPRSS2, an essential protease for ACE-2 virus receptor ...
Martins R +11 more
europepmc +2 more sources
Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin. [PDF]
The aim of the present study was the development and subsequent validation of a simple, precise and stability-indicating reversed phase HPLC method for the simultaneous determination of guaifenesin, terbutaline sulphate and bromhexine hydrochloride in the presence of their potential impurities in a single run.
Porel A, Haty S, Kundu A.
europepmc +4 more sources
Simultaneous determination of salbutamol sulphate and bromhexine hydrochloride in tablets by reverse phase liquid chromatography. [PDF]
Se ha desarrollado un método simple de cromatografía líquida de fase inversa y posteriormente se ha validado para la determinación simultánea de sulfato de salbutamol y clorhidrato de bromhexina. La separación se llevó a cabo utilizando una fase móvil que consistía en acetonitrilo, metanol y amortiguador de fosfato, pH 4 en la relación 60:20:20 v/v. La
Pai PN +4 more
europepmc +4 more sources
Development of a rapid method for the simultaneous determination of aminophylline, doxofylline, bromhexine, and ambroxol by HPLC [PDF]
Introduction: Antitussive and expectorant drugs such as aminophylline (APL), doxofylline (DXL), bromhexine hydrochloride (BXH), and ambroxol hydrochloride (AXH), either individually or in combination, are widely used in the prevention and treatment of ...
Xia Meng +4 more
doaj +2 more sources
Comparative Pharmacokinetics and Egg Residues of Amoxicillin, Single and in Combination with Bromhexine, in Laying Hens [PDF]
The need for antibiotics in commercial laying hens is increasing owing to intensive farming systems. Amoxicillin trihydrate (AMX), an aminopenicillin β-lactam antibiotic, exerts broad bactericidal activity.
Jeong-Won Kim +8 more
doaj +2 more sources
Endobronchial chondroma with ossification mimicking chronic obstructive pulmonary disease: a case report [PDF]
BackgroundEndobronchial chondroma is a rare benign mesenchymal tumour, and its etiology remains not entirely understood. Due to the tumour’s slow growth rate, the early stages of the disease often present with atypical or nonspecific clinical symptoms ...
Xiaoling Huang +6 more
doaj +2 more sources

