Results 41 to 50 of about 1,283 (170)

4-Amino-5-{[cyclohexyl(methyl)amino]methyl}isophthalonitrile

IUCrData, 2019
The title compound, C16H20N4, was synthesized by cyanation of bromhexine. The compound crystallizes with two unique molecules in the asymmetric unit. The substituted aniline and cyclohexane rings are inclined to one another by 37.26 (6)° in one molecule ...
Muhammad Sharif, Rauf Razzaq, Ralf Jackstell, Anke Spannenberg   +3 more
doaj   +1 more source

Trueperella pyogenes–Associated Acute Pneumonia in Korean Native Calves

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Trueperella pyogenes can cause a wide range of suppurative infections, including urogenital and mammary infections, liver abscesses and pneumonia. This case report demonstrates Trueperella pyogenes as a primary cause of bovine respiratory disease in Korean native calves.
Min‐Jeong Ji, Youngjun Kim, Byoung‐Soo Kim, Jongho Kim, Kyoung‐Seong Choi   +4 more
wiley   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

Journal of Small Animal Practice, Volume 67, Issue 5, Page 460-470, May 2026.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry, R. Rizzo, Y. Tan, A. M. Boag, J. Del‐Pozo, G. A. Woods   +5 more
wiley   +1 more source

The role of peripheral serotonin in SARS‐CoV‐2 infectivity, COVID‐19 treatment and long COVID

Immunology &Cell Biology, Volume 104, Issue 4, Page 368-376, April 2026.
In this article, we discuss how SARS‐CoV‐2 infects the gastrointestinal tract, that enterochromaffin cells, the source of circulating serotonin, uniquely express viral entry receptors. We examine how this infection disrupts gut‐derived serotonin, contributing to gastrointestinal symptoms and disease severity, and link elevated plasma serotonin to COVID‐
Daniel W Thorpe, Lauren A Jones, Alyce M Martin, Rosemary A Coleman, Caitlin Allman, Rochelle A Peterson, Damien J Keating   +6 more
wiley   +1 more source

Spectrophotometric Determination of Bromhexine-HCl by Using Prepared Silver Nanoparticles

مجلة بغداد للعلوم
In this study, a new, simple, and rapid method was developed for determining Bromhexine-HCl using silver nanoparticles. The solution of silver nanoparticles has a yellow color which has absorbency at a wavelength of 404 nm.
Zainab Noori, Muna M. Khudhair
doaj   +1 more source

Non‐Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review

Fundamental &Clinical Pharmacology, Volume 40, Issue 2, March 2026.
ABSTRACT Background Repositioning offers a cost‐effective approach to discovering new therapeutic applications for existing medications. Ambroxol, primarily used as a mucolytic for respiratory diseases, has demonstrated anti‐inflammatory, analgesic, and antioxidant properties, suggesting potential benefits in non‐pulmonary conditions.
Michelline Joana Tenório Albuquerque Madruga Mesquita, Anne Caroline Silva Nogueira da Cruz, Rafael de Abreu Lima, Joana Tenório‐Meireles, Arney José Nogueira Farias, Isabela Nogueira Santos, Gustavo Frota, Taciana Gabrielle Pinheiro de Moura Carvalho, Rafael Antônio Freire Carvalho, Jorge Antônio Meireles‐Teixeira, Tereza Prazeres, Rafael Cardoso Carvalho, Maria do Socorro de Sousa Cartágenes, João Batista Santos Garcia   +13 more
wiley   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Thermo-Analytical and Compatibility Study with Mechanistic Explanation of Degradation Kinetics of Ambroxol Hydrochloride Tablets under Non-Isothermal Conditions

Pharmaceutics, 2021
Ambroxol hydrochloride (AMB), used as a broncho secretolytic and an expectorant drug, is a semi-synthetic derivative of vasicine obtained from the Indian shrub Adhatoda vasica. It is a metabolic product of bromhexine. The paper provides comprehensive and
Dijana Jelić, Snežana Papović, Milan Vraneš, Slobodan Gadžurić, Silvia Berto, Eugenio Alladio, Dragana Gajić, Bojan Janković   +7 more
doaj   +1 more source

Solvent‐Free Mechanocatalytic Reduction of Nitro Compounds with Hydrogen Gas and its Application in the Synthesis of Drugs and their Intermediates

Advanced Synthesis &Catalysis, Volume 367, Issue 19, October 15, 2025.
A solvent‐free mechanochemical reduction of nitro compounds using hydrogen gas is presented. In addition to enabling the synthesis of a variety of functionalized aniline derivatives, the method has been scaled up to gram quantities, evaluated for trace metal impurities, and applied to the synthesis of pharmaceutical compounds and their precursors.
Samarth Bhatnagar, Michael Felderhoff, Jan‐Hendrik Schöbel   +2 more
wiley   +1 more source

Investigation Into the Effect of Vaccination on Pulmonary Involvements in Patients With COVID‐19 Infection, Based on High‐Resolution CT Imaging

The Clinical Respiratory Journal, Volume 19, Issue 9, September 2025.
Patients with COVID‐19 pneumonia: Vaccinated versus non‐vaccinated. ABSTRACT Background COVID‐19 infection has been a major pandemic of this century, causing deaths, economic hardship, and poverty worldwide. At the moment, vaccination remains the most effective measure against this health challenge.
Elahe Amani, Bentolhoda Otroshi, Mohsen Tabatabaie, Azam Moslemi, Shiva Shabani   +4 more
wiley   +1 more source