Thermo-Analytical and Compatibility Study with Mechanistic Explanation of Degradation Kinetics of Ambroxol Hydrochloride Tablets under Non-Isothermal Conditions [PDF]
Pharmaceutics, 2021 Ambroxol hydrochloride (AMB), used as a broncho secretolytic and an expectorant drug, is a semi-synthetic derivative of vasicine obtained from the Indian shrub Adhatoda vasica. It is a metabolic product of bromhexine. The paper provides comprehensive and
Bojan Janković +2 more
exaly +6 more sources
Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis [PDF]
Frontiers in Pharmacology, 2019 Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS.
Alexandra Bouscary +12 more
doaj +3 more sources
Clinical study on modified Shenzhe Zhenqi Decoction combined with ambroxol hydrochloride in the treatment of severe pneumonia [PDF]
Frontiers in PhysiologyObjectiveThis study aimed to evaluate the clinical efficacy of modified Shenzhe Zhenqi Decoction combined with ambroxol hydrochloride in treating severe pneumonia.MethodsThis was a single-center, prospective, double-blind, randomized controlled trial.
Ting Lin, Cunyi Shen
exaly +4 more sources
The efficacy of nebulized budesonide and ambroxol hydrochloride in treating pediatric community-acquired pneumonia and their impact on clinical characteristics and inflammatory markers [PDF]
Journal of Health, Population and NutritionPurpose To evaluate the therapeutic efficacy of intravenous amoxicillin clavulanate potassium combined with nebulized budesonide and ambroxol hydrochloride in pediatric community-acquired pneumonia (CAP) and its impact across various microbial strains ...
Xiaoqin Zhang +4 more
doaj +3 more sources
The combination of astragalus injection and ambroxol hydrochloride in the adjuvant treatment of COPD: a systematic review and meta-analysis [PDF]
Scientific Reports, 2023 Chronic obstructive pulmonary disease (COPD) is a severe condition that leads to premature mortality and places a significant financial burden on healthcare systems.
Zubing Zhou +5 more
doaj +2 more sources
Beneficial effects of ambroxol hydrochloride on pentylenetetrazol-induced convulsion model in rats
Medicine Science, 2020 In present experimental study, we purposed to research if ambroxol would have beneficial acute effects on PTZ-induced convulsions by EEG records. 48 rats were randomly divided into two groups; group A for EEG recordings and B for behavioral evaluations ...
Eda Sunnetci +3 more
doaj +2 more sources
Ambroxol hydrochloride alleviates acute lung injury induced by gastric juice aspiration in rats [PDF]
Jichu yixue yu linchuang, 2022 Objective To investigate the therapeutic and protective effect of ambroxol hydrochloride on acute lung injury caused by aspiration of gastric juice in rats.
CUI Yi-yao, WANG Feng, LYU Xiao-shuo, LIU Chun-quan, XU Kai-kai, CUI Yong
doaj +2 more sources
Meta-analysis of the efficacy of budesonide and ambroxol hydrochloride inhalation in children with pneumonia and their effects on inflammatory response [PDF]
Heliyon, 2023 Childhood pneumonia, often caused by acute upper respiratory tract infections or bronchitis, is one of the leading causes of mortality in children. Nebulized inhalation, as a low-risk treatment method, has garnered significant attention.
Huanan Shen, Xingni Zhao, Liangyin Xu
doaj +2 more sources
Comparative Study for Spectrofluorimetric Determination of Ambroxol Hydrochloride Using Aluminum Metal Transfer Chelation Complex and Biogenic Synthesis of Aluminum Oxide Nanoparticles Using Lavandula spica Flowers Extract [PDF]
Molecules, 2023 The existing study pronounces two newly developed spectrofluorimetric probes for the assay of ambroxol hydrochloride in its authentic and commercial formulations using an aluminum chelating complex and a biogenically mediated and synthesized aluminum ...
Najla S. Al-Humud +3 more
doaj +2 more sources
Ambroxol hydrochloride spray (Luo Runchang®) in the treatment of acute respiratory infectious diseases: a prospective, multicenter, open label, randomized controlled study [PDF]
Frontiers in PediatricsPurposeCough and sputum are the most common clinical symptoms of acute respiratory tract infection. Ambroxol is a mucolytic expectorant commonly used in clinical practice.
Lu Cheng +11 more
doaj +2 more sources