Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts [PDF]
A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (APP) scaffold has been synthesized. The key step involved a totally stereocontrolled C-Michael addition of a serine-equivalent C-nucleophile to tri-O ...
Avenoza, A. +9 more
core +1 more source
Rapid, precise, accurate, specific and sensitive reverse phase liquid chromatographic and absorbance ratio spectrophotometric methods have been developed for the simultaneous analysis of ambroxol hydrochloride and cetirizine hydrochloride in their tablet formulation. The chromatographic methods were standardized using a HIQ SIL-C(18) column (250×4.6 mm
Bhatia, Neela M. +4 more
openaire +3 more sources
Drug-induced anaphylaxis in China: a 10 year retrospective analysis of the Beijing Pharmacovigilance Database [PDF]
Background Few studies on the causes of drug-induced anaphylaxis (DIA) in the hospital setting are available. Objective We aimed to use the Beijing Pharmacovigilance Database (BPD) to identify the causes of DIA in Beijing, China.
Li, Xiaotong +7 more
core +1 more source
Preparation and evaluation of microencapsulated fast melt tablets of ambroxol hydrochloride
Natural resources in general and plant materials in particular are receiving more attention due to their safety as pharmaceutical excipients. Present work assessed the potential of a natural polysaccharide, pectin to mask the bitter taste of ambroxol hydrochloride, by microencapsulation technique, and its possibility to formulate as a fast ...
Jacob, S., Shirwaikar, A.
openaire +3 more sources
Polymorphism of spironolactone: An unprecedented case of monotropy turning to enantiotropy with a huge difference in the melting temperatures [PDF]
Postprint (author's final ...
Barrio Casado, María del +4 more
core +4 more sources
Determination of ambroxol hydrochloride using dithiocarbamic acid colorimetric method
A new simple, colorimetric method was developed on the basis of a chemical reaction of amine group in ambroxol hydrochloride with carbon disulphide to form dithiocarbamic acid, which on further reaction with cupric chloride forms a colored copper chelate.
PNS Pai +3 more
openaire +1 more source
Formulation and Evaluation of Levocetirizine Dihydrochloride and Ambroxol Hydrochloride Lozenges
The present work aims to formulate and evaluate levocetirizine dihydrochloride and ambroxol hydrochloride hard candy lozenges to produce a slow-release of drugs for the management of cold and cough. The lozenges were prepared using sucrose, liquid glucose, hydroxyethylcellulose, and hydroxypropyl methylcellulose K4M by heating and congealing method ...
R Reddy Thout +3 more
openaire +1 more source
Mengoptimalkan Analisis Ambroxol Hidroklorida: Pendekatan Kromatografi Cair Kinerja Tinggi (Hplc) yang Komprehensif [PDF]
Ambroxol hidroklorida adalah senyawa yang umum digunakan dalam formulasi sediaan farmasetika, terutama tablet, sebagai agen ekspektoran dan mukolitik. Penelitian ini menyoroti pentingnya pemantauan kadar Ambroxol hidroklorida dalam sediaan tablet untuk ...
Hidayah, Himyatul +3 more
core +2 more sources
ПРИМЕНЕНИЕ МУКОАКТИВНЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ В ПРАКТИКЕ ТЕРАПЕВТА
Russia is among the countries where using of mucolytic drugs in clinical practice is widespread. In chronic bronchitis, chronic obstructive pulmonary disease, acute respiratory syndrome with prolonged cough, pneumonia, tuberculosis and many other ...
Ф. Т. Малыхин +2 more
doaj +1 more source
Novel Ratio Subtraction and Isoabsorptive Point Methods for Determination of Ambroxol Hydrochloride and Doxycycline in their Combined Dosage Form: Development and Validation [PDF]
Purpose: To develop and validate two innovative spectrophotometric methods used for the simultaneous determination of ambroxol hydrochloride and doxycycline in their binary mixture.Methods: Ratio subtraction and isoabsorptive point methods were used for ...
Darwish, HA, El Bayoumi, A, Metwally, FH
core +2 more sources

