Results 71 to 80 of about 1,694 (202)

Pharmacokinetics and Relative Bioavailability of Ambroxol Hydrochloride Aerosol and Injection [PDF]

American Journal of Clinical and Experimental Medicine, 2015
To compare the pharmacokinetics and relative bioavailability of ambroxol hydrochloride (AH) aerosol and injection, the volunteers were subjected to single-dose crossover inhalation (injection) of 100 mg AH aerosol (injection). The drug concentrations in plasma were determined by HPLC. The areas under curve (AUC) of the two formulations were compared by
openaire   +1 more source

Signal Detection of Pediatric Drug–Induced Coagulopathy Using Routine Electronic Health Records

Frontiers in Pharmacology, 2022
Background: Drug-induced coagulopathy (DIC) is a severe adverse reaction and has become a significantly increased clinical problem in children. It is crucial to the detection of the DIC safety signal for drug post-marketing scientific supervision ...
Xiaolu Nie, Xiaolu Nie, Xiaolu Nie, Yuncui Yu, Lulu Jia, Houyu Zhao, Zhenping Chen, Liqiang Zhang, Xiaoling Cheng, Yaqi Lyu, Wang Cao, Xiaoling Wang, Xiaoxia Peng, Xiaoxia Peng   +13 more
doaj   +1 more source

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

Pediatric Investigation, Volume 9, Issue 3, Page 205-220, September 2025.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics, China Medical Education Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of China Non‐public Medical Institution Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China Medical News and Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, Global Pediatric Respiratory Alliance, Beijing Hairun Charity Foundation   +16 more
wiley   +1 more source

Ambroxol effects in glucocerebrosidase and -synuclein transgenic mice [PDF]

, 2016
Objective. Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase.
Bezard, E, Daly, L, Migdalska-Richards, A, Schapira, AHV   +3 more
core  

DISSOLUTION PROFILE OF AMBROXOL HCl TABLET WITH ADDITIONAL VARIATIONS OF LUDIPRESS® AND LACTOSE USING THE DIRECT PRESS METHOD [PDF]

, 2020
Objective: The drug will provide a therapeutic effect when dissolved so that it is easily absorbed. The process of dissolving drugs is called dissolution.
GOZALI, DOLIH, MUSTARICHIE, RESMI, PRIAMBODO, DRADJAD   +2 more
core   +3 more sources

Broaden properties of ambroxol hydrochloride as an antibiofilm compound

Revista Argentina de Microbiología
Biofilm-associated microorganisms can cause many infections and are an important cause of resistance to several antimicrobials. The antibiotic crisis has led to a pressing need for new therapeutic tools. Ambroxol is frequently used as a mucolytic agent in respiratory diseases with increased mucus production.
María J. González, Michela Lain, Victoria Iribarnegaray, Luciana Robino, Paola Scavone   +4 more
openaire   +2 more sources

Molecular Mechanisms of Chronic Pain and Therapeutic Interventions

MedComm, Volume 6, Issue 8, August 2025.
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li, Xing Li, Jieqiong Liu, Rao Sun, Yingze Ye, Hongbing Xiang, Fang Luo, Shiyong Li, Ailin Luo   +8 more
wiley   +1 more source

Spectrophotometric Determination of Drugs by Means of Schiff Base Formation: A Review [PDF]

, 2022
Molecules that do not ordinarily absorb radiation in the visible region of the spectrum can be made to do so by introducing chromogens that facilitate electronic transitions.
Bozhanov, Stanislav, Maslarska, Vania, Smerikarova, Miglena, Tsvetkova, Boyka   +3 more
core   +2 more sources

SPECTROPHOTOMETRIC DETERMINATION OF TRAMADOL HCI, AMBROXOL HCI AND CLIDINIUM BROMIDE IN PHARMACEUTICAL FORMULATIONS

Zagazig Journal of Pharmaceutical Sciences, 2006
Two simple, sensitive and accurate spectrophotometric methods have been established for the determination of clidinium bromide (CBr), ambroxol hydrochloride (AX) and tramadol hydrochloride (TD) using methyl orange (MO) and bromocresol purple (BCP) The ...
Alaa Amin , Wafaa Hassan , Ragaa EL-Sheikh , Ayman Gouda   +3 more
doaj   +1 more source

α‐Synuclein in Parkinson's Disease: From Bench to Bedside

Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.
ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini, Vanessa D'Antongiovanni, Giovanni Palermo, Luca Antonioli, Matteo Fornai, Roberto Ceravolo, Nunzia Bernardini, Pascal Derkinderen, Carolina Pellegrini   +8 more
wiley   +1 more source