Results 151 to 160 of about 274,568 (352)

Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension : a protocol for a factorial randomized controlled trial [PDF]

, 2019
Background: Thiazide diuretics have demonstrated favorable blood pressure lowering efficacy, but the equivalent doses of their more common agents, chlorthalidone and hydrochlorothiazide, are still unclear.
Bottino, Leonardo Grabinski, Ferrari, Felipe, Fuchs, Flávio Danni, Fuchs, Sandra Cristina Pereira Costa, Helal, Lucas Crescenti Abdalla Saad, Martins, Vitor Magnus   +5 more
core  

Associations of Central Arterial Stiffness With Brain White Matter Integrity and Gray Matter Volume in MRI Across the Adult Lifespan

Journal of Magnetic Resonance Imaging, EarlyView.
Background Central arterial stiffening is associated with brain white matter (WM) damage and gray matter (GM) volume loss in older adults, but little is known about this association from an adult lifespan perspective. Purpose To investigate the associations of central arterial stiffness with WM microstructural organization, WM lesion load, cortical ...
Junyeon Won, Tsubasa Tomoto, Kevin Shan, Takashi Tarumi, Rong Zhang   +4 more
wiley   +1 more source

Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial

Journal of Clinical Pharmacy and Therapeutics, Volume 47, Issue 12, Page 2230-2236, December 2022., 2022
The rate of hypotension was 36.5% in the remimazolam group and 69.6% in the propofol group (p < 0.001). The remimazolam group also had a lower rate of bradycardia (1.5% vs. 8.5%, p < 0.001) and respiratory depression (4.5% vs. 10.0%, p < 0.05). Abstract Background and Objective Propofol is the most commonly used sedative in gastrointestinal endoscopic ...
Kejian Lu, Shanshan Wei, Wenwen Ling, Yanxia Wei, Xuelian Ran, Huageng Huang, Meixu Wang, Ning Wei, Yanying Liao, Zailing Qin, Meitao Pan, Qimei Wei, Liuhui Fu, Boquan Xiong, Chendong Ma, Jun Jiang, Yanjuan Huang   +16 more
wiley   +1 more source

Prognostic value of ambulatory blood pressure monitoring in refractory hypertension: a prospective study.

HYPERTENSION, 1998
The objective of this study was to establish whether ambulatory blood pressure offers a better estimate of cardiovascular risk than does its clinical blood pressure counterpart in refractory hypertension.
J. Redón, C. Campos, Maria L. Narciso, J. Rodicio, J. Pascual, L. Ruilope   +5 more
semanticscholar   +1 more source

Deadline Effect in Stroke Patient Care: A Temporal Motivation Theory Perspective of Process Management

Journal of Operations Management, EarlyView.
ABSTRACT Stroke is a highly time‐sensitive medical emergency, and earlier treatment is crucial. Drawing on Temporal Motivation Theory, we investigate a “deadline effect” in stroke care and analyze how two deadlines, that is, a medically oriented one (administering Tissue Plasminogen Activator, TPA, within 4.5 h of symptom onset) and a goal‐oriented one
Brandon Lee, Seokjun Youn, Lawrence Fredendall   +2 more
wiley   +1 more source

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan, Nick Huffman, Xiaojuan Li, Anukriti Sharma, Carl S. Winalski, Eric T. Ricchetti, Kathleen Derwin, Suneel S. Apte, Daniel Rotroff, Carl Y. Saab, Nicolas S. Piuzzi   +10 more
wiley   +1 more source

Severe distinct dysautonomia in RFC1‐related disease associated with Parkinsonism

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 311-315, December 2022., 2022
Abstract Biallelic repeat expansions in replication factor C subunit 1 (RFC1) have recently been found to cause cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS). Additional features that have been described include Parkinsonism and a multiple system atrophy (MSA)‐like syndrome.
Christopher J. Record, Rana Alnasser Alsukhni, Riccardo Curro, Diego Kaski, John S. Rubin, Huw R. Morris, Andrea Cortese, Valeria Iodice, Mary M. Reilly   +8 more
wiley   +1 more source

Home care in Germany during the COVID‐19 pandemic: A neglected population?

Journal of Nursing Scholarship, Volume 55, Issue 1, Page 215-225, January 2023., 2023
Abstract Introduction Older persons and those with pre‐existing conditions are at the biggest risk for severe illness and death from COVID‐19. In Germany, more than 3.3 million people out of this population receive care in their own homes. User representatives and nurses have criticized health policy during the COVID‐19 pandemic as inappropriate for ...
Thomas Fischer
wiley   +1 more source

Guidelines for the clinical use of 24 hour ambulatory blood pressure monitoring (ABPM) (JCS 2010): – digest version –.

Circulation Journal, 2012
Purpose of the Guidelines The Guidelines for the Clinical Use of 24 Hour Ambulatory Blood Pressure Monitoring (ABPM) was first released as a 1998–1999 Japanese Circulation Society (JCS) report to describe the results of clinical research and clinical ...
K. Shimada, Y. Imai, K. Kario, Y. Kawano, G. Kimura, I. Kuwajima, Yasumasa Yamamoto, Yoshinori Doi, K. Kikuchi, K. Otsuka, T. Ozawa, I. Saito   +11 more
semanticscholar   +1 more source

Medical–surgical nurse leaders' experiences with safety culture: An inductive qualitative descriptive study

Journal of Nursing Management, Volume 30, Issue 7, Page 2781-2790, October 2022., 2022
Abstract Aim The aim of this study is to describe safety culture as experienced by medical–surgical nurse leaders. Background Safety culture remains a barrier in safer patient care. Nurse leaders play an important role in creating and supporting a safety culture. Methods We used an inductive qualitative descriptive study using semistructured interviews,
Lisa Harton, Lisa Skemp
wiley   +1 more source