Results 141 to 150 of about 58,618 (265)

Complement-Modulating Mechanisms of Ginkgo biloba Extract in Dry AMD: Insights From Molecular Docking and Dynamics Simulations. [PDF]

Transl Vis Sci Technol
Huang T, Jiang D, Wang D, Dong Z, Hou Y, Li X, Deng X, Liu X.   +7 more
europepmc   +1 more source

Effect of Intramuscular Adrenaline on Histamine‐Induced Hypotension: A Randomised Placebo‐Controlled Pilot Trial

Allergy, EarlyView.
Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach, Al Medina Dizdarevic, Thorsten Bischof, Christa Firbas, Alexander Taschner, Eva‐Luise Ritter‐Hobl, Barbara Steinlechner, Eva Fischer, Lorenz Sonnberger, Georg Gelbenegger, Jolanta M. Siller‐Matula, Christian Schoergenhofer, Bernd Jilma   +12 more
wiley   +1 more source

Decoding the Factor H-Related Proteins: Gatekeepers of Complement Dysregulation in AMD. [PDF]

Eur J Immunol
Tang J, Zgoda N, Clark SJ.
europepmc   +1 more source

Mesopic microperimetry in Stargardt disease: Application and reliability

Acta Ophthalmologica, EarlyView.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra, Jeroen A. A. H. Pas, Patty P. A. Dhooge, Steffen Schmitz‐Valckenberg, Maurizio Battaglia Parodi, Philipp Herrmann, Frank G. Holz, Andrew J. Lotery, Katarina Stingl, Thomas H. Wheeler‐Schilling, Camiel J. F. Boon, Carel B. Hoyng, Soraprazan Consortium   +12 more
wiley   +1 more source

Revisiting retinal and macular degeneration in the genomics era. [PDF]

Nat Rev Genet
Swaroop A, Roska B.
europepmc   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Dietary Patterns and Age-Related Macular Degeneration: A Matched Case-Control Study. [PDF]

Nutrients
Azalati MM, Jiang H, Zhang K, Kong L, Wang L, Li Z, Fan Y, Chen F, Ma L, Zhang W.   +9 more
europepmc   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Rapid Macular Thinning as a Biomarker for Geographical Atrophy. [PDF]

Clin Ophthalmol
Cukurova F, Ramsey DJ.
europepmc   +1 more source

Association of treated neovascular AMD with disability and mood disorders: A longitudinal nationwide study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the associations of treated neovascular AMD with the risk of disability, falls, fractures and mood disorders in a large sample representative of the French population. Methods Analyses were based on 77 582 individuals belonging to the ‘Echantillon Généraliste des Bénéficiaires’, a 1/97 random sample of the French population,
Cécile Delcourt, Emilie Hucteau, Sarra Gattoussi, Karine Pérès, Marie‐Noelle Delyfer, Catherine Helmer, Jean‐François Korobelnik   +6 more
wiley   +1 more source