Results 221 to 230 of about 100,399 (259)

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Adaptive and degenerative mitochondrial remodeling define distinct redox states in age-related macular degeneration. [PDF]

Redox Biol
Giulivi C, Villafuerte-Trisolini C, Greenblatt ZL, Dang J, Tork A, Mullah R, Le S, Min A, Nair M, Vorkapich A, Tran HA, Doyle E, Law A, O'Keefe O, Wu A, Shibata B, Ripolles-Garcia A, Thomasy SM, Harris RA, Chen R, Liu YA, Yiu G.   +21 more
europepmc   +1 more source

VEGF‐A Antisense Oligonucleotide Therapy Inhibits Corneal Neovascularisation and Enhances Graft Survival in Murine High‐Risk Corneal Transplantation

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate, for the first time, whether an unconjugated VEGF‐A antisense oligonucleotide (ASO) can inhibit corneal neovascularisation and improve graft survival in a murine high‐risk corneal transplantation model. Methods A suture‐induced corneal neovascularisation model was established in BALB/c mice, followed by high‐risk ...
Wei Zhang, Christian Weile, Christoph Ullmer, Sascha Fauser, Felix Bock, Claus Cursiefen   +5 more
wiley   +1 more source

The role of NLRP3 inflammasome in age-related macular degeneration: mechanisms and therapeutic prospects. [PDF]

Front Aging Neurosci
Zhu M, Yu W.
europepmc   +1 more source

Deep Phenotyping in ReNU Syndrome Identifies a Recognizable Age‐Dependent Clinical Trajectory

Clinical Genetics, EarlyView.
Longitudinal evaluation of 11 individuals with ReNU syndrome revealed an age‐dependent multisystem trajectory. This longitudinal description may help clinicians anticipate changing needs in feeding, growth, neurological, visual, communication, behavioral, and orthopedic care. ABSTRACT Pathogenic variants in the noncoding gene RNU4‐2 cause ReNU syndrome,
Nadja Pekkola Pacheco, Malin Kvarnung, Anna Hammarsjö, Daniel Nilsson, Bianca Tesi, Britt Marie Anderlid, Giedre Grigelioniene, Maria Johansson Soller, Liselot van der Laan, Charlotte Willfors, Charlotta Ingvoldstad Malmgren, Anna Lindstrand, Tommy Stödberg, Ann Nordgren, Angelica Maria Delgado‐Vega   +14 more
wiley   +1 more source

Elevated Food Inflammation Scores of individuals is a significant risk factor for age-related macular degeneration in adults in the United States: Evidence from NHANES. [PDF]

Medicine (Baltimore)
Song Y, Ji H, Xie D, Huang F, Yang L.
europepmc   +1 more source

Splatshop: Efficiently Editing Large Gaussian Splat Models

Computer Graphics Forum, EarlyView.
Abstract We present Splatshop, a highly optimized toolbox for interactive editing (selection, deletion, painting, transformation, …) of 3D Gaussian Splatting models. Utilizing a comprehensive collection of heuristic approaches, we carefully balance between exact and fast rendering to enable precise editing without sacrificing real‐time performance. Our
Markus Schütz, Christoph Peters, Florian Hahlbohm, Elmar Eisemann, Marcus Magnor, Michael Wimmer   +5 more
wiley   +1 more source

Association between vitamin B6 metabolism and the prevalence of age-related macular degeneration: A cross-sectional analysis of National Health and Nutrition Examination Survey (NHANES). [PDF]

Medicine (Baltimore)
Tang M, Sun S, Liu Y, Dong L.
europepmc   +1 more source

SDFs from Unoriented Point Clouds using Neural Variational Heat Distances

Computer Graphics Forum, EarlyView.
We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier, Florine Hartwig, Josua Sassen, Sergio Conti, Mirela Ben‐Chen, Martin Rumpf   +5 more
wiley   +1 more source

ORBIT-AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age-Related Macular Degeneration in Multi-Cohorts. [PDF]

Adv Sci (Weinh)
Cui X, Wen D, Yu-Wai-Man P, Li X.
europepmc   +1 more source