Results 21 to 30 of about 529 (192)

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Multifunctional Tailoring of Fertilizer Composites Directly Derived From Phosphate Rock

Advanced Science, EarlyView.
A novel phosphorus‑sulfur mixed acid with urea (PSU) activation system converts low‑grade phosphate rock (LPR) into multifunctional fertilizer composites (MFCs). MFCs feature porous structures, high nutrient‑activation efficiency, superior slow‑release, and enhanced crop growth, offering a sustainable solution for integrated nutrient management and ...
Zenglian Qi, Jianchao Wang, Lulu Chen, Zhenya Lu, Guodong Wang, Hang Ma, Cuihong Hou, Xinxin Wang, Wenqi Ma, Changzhou Wei, Jianbo Shen, Fusuo Zhang, Minghao Zhuang, Chengdong Huang   +13 more
wiley   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Distorsions de ségrégation et amélioration génétique des plantes (synthèse bibliographique)

Biotechnologie, Agronomie, Société et Environnement, 2012
Segregation distortions and their consequences for plant breeding: a review. Distortion of allele segregation is a phenomenon common to all living organisms.
Diouf, FBH., Mergeai, G.
doaj  

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

Effect of mulching systems on fruit quality and phytochemical composition of newly developed strawberry lines

Agricultural and Food Science, 2012
The effects of three mulching systems on total yield, average yield per plant, average fruit weight, soluble solids content (SSC), titratable acidity (TA), firmness and oxygen radical absorbance capacity (ORAC) of two newly developed lines (‘Orléans’ and
Li Fan, Valentine Roux, Claudine Dubé, Dennis Charlebois, Shutian Tao, Shahrokh Khanizadeh   +5 more
doaj  

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source