Results 41 to 50 of about 6,798 (252)

Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes

open access: yesFrontiers in Cell and Developmental Biology, 2020
Dental epithelial stem cells give rise to four types of dental epithelial cells: inner enamel epithelium (IEE), outer enamel epithelium (OEE), stratum intermedium (SI), and stellate reticulum (SR).
Yuta Chiba   +11 more
doaj   +1 more source

Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation

open access: yesFrontiers in Physiology, 2017
The transport of mineral ions from the enamel organ-associated blood vessels to the developing enamel crystals involves complex cargo packaging and carriage mechanisms across several cell layers, including the ameloblast layer and the stratum intermedium.
Mirali Pandya   +7 more
doaj   +1 more source

PENGARUH SUSU IBU HAMIL TERHADAP EKSPRESI KALLIKREIN-RELATED PEPTIDASE-4 (KLK-4) PADA SEL AMELOBLAS DALAM TUMBUH KEMBANG GIGI

open access: yesODONTO: Dental Journal, 2020
Background: Tooth development during the embryonic period is a complex process that needs enough nutrition for the formation of healthy dental tissue. Kallikrein-related peptidase-4 (KLK-4) is a serine proteinase secreted by ameloblast during transition ...
Salma Samia   +2 more
doaj   +1 more source

The effect of inhibiting p38 MAPK on the expression of genes related to enamel development in mice

open access: yes口腔疾病防治, 2021
Objective To study the effect of p38 mitogen activated protein kinase (p38 MAPK) on the expression of genes related to enamel development in the enamel epithelium and to provide a basis for the study of the molecular mechanism of enamel development ...
LUO Xiaona   +4 more
doaj   +1 more source

No Change in Bicarbonate Transport but Tight-Junction Formation Is Delayed by Fluoride in a Novel Ameloblast Model

open access: yesFrontiers in Physiology, 2017
We have recently developed a novel in vitro model using HAT-7 rat ameloblast cells to functionally study epithelial ion transport during amelogenesis. Our present aims were to identify key transporters of bicarbonate in HAT-7 cells and also to examine ...
Róbert Rácz   +9 more
doaj   +1 more source

DataSheet1_Epiprofin Transcriptional Activation Promotes Ameloblast Induction From Mouse Induced Pluripotent Stem Cells via the BMP-Smad Signaling Axis.docx

open access: yes, 2022
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption.
Hiroshi Egusa (36538)   +8 more
core   +1 more source

Temporal and spatial expression of TGF-b 2 in tooth crown development in mouse first lower molar

open access: yesEuropean Journal of Histochemistry, 2009
Transforming Growth Factor b2 (TGF-b2) is involved in the regulation of many important cellular processes during tooth development. In this study we systematically characterized the expression pattern of TGF-b2 in vivo and further analyzed its possible ...
JY Li, B Hu, XJ Wang, SL Wang
doaj   +1 more source

Calcium Sets the Clock in Ameloblasts

open access: yesFrontiers in Physiology, 2020
BackgroundStromal interaction molecule 1 (STIM1) is one of the main components of the store operated Ca2+ entry (SOCE) signaling pathway. Individuals with mutated STIM1 present severely hypomineralized enamel characterized as amelogenesis imperfecta (AI)
Raed Said   +5 more
doaj   +1 more source

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice

open access: yesFrontiers in Physiology, 2023
Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said   +10 more
doaj   +1 more source

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation

open access: yesFrontiers in Physiology, 2021
Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling to regulate organogenesis.
Aya Yamada   +12 more
doaj   +1 more source

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