Results 41 to 50 of about 6,798 (252)
Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes
Dental epithelial stem cells give rise to four types of dental epithelial cells: inner enamel epithelium (IEE), outer enamel epithelium (OEE), stratum intermedium (SI), and stellate reticulum (SR).
Yuta Chiba +11 more
doaj +1 more source
Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation
The transport of mineral ions from the enamel organ-associated blood vessels to the developing enamel crystals involves complex cargo packaging and carriage mechanisms across several cell layers, including the ameloblast layer and the stratum intermedium.
Mirali Pandya +7 more
doaj +1 more source
Background: Tooth development during the embryonic period is a complex process that needs enough nutrition for the formation of healthy dental tissue. Kallikrein-related peptidase-4 (KLK-4) is a serine proteinase secreted by ameloblast during transition ...
Salma Samia +2 more
doaj +1 more source
The effect of inhibiting p38 MAPK on the expression of genes related to enamel development in mice
Objective To study the effect of p38 mitogen activated protein kinase (p38 MAPK) on the expression of genes related to enamel development in the enamel epithelium and to provide a basis for the study of the molecular mechanism of enamel development ...
LUO Xiaona +4 more
doaj +1 more source
We have recently developed a novel in vitro model using HAT-7 rat ameloblast cells to functionally study epithelial ion transport during amelogenesis. Our present aims were to identify key transporters of bicarbonate in HAT-7 cells and also to examine ...
Róbert Rácz +9 more
doaj +1 more source
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption.
Hiroshi Egusa (36538) +8 more
core +1 more source
Temporal and spatial expression of TGF-b 2 in tooth crown development in mouse first lower molar
Transforming Growth Factor b2 (TGF-b2) is involved in the regulation of many important cellular processes during tooth development. In this study we systematically characterized the expression pattern of TGF-b2 in vivo and further analyzed its possible ...
JY Li, B Hu, XJ Wang, SL Wang
doaj +1 more source
Calcium Sets the Clock in Ameloblasts
BackgroundStromal interaction molecule 1 (STIM1) is one of the main components of the store operated Ca2+ entry (SOCE) signaling pathway. Individuals with mutated STIM1 present severely hypomineralized enamel characterized as amelogenesis imperfecta (AI)
Raed Said +5 more
doaj +1 more source
Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice
Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said +10 more
doaj +1 more source
Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling to regulate organogenesis.
Aya Yamada +12 more
doaj +1 more source

