Results 1 to 10 of about 3,701 (166)

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Impact of Amelogenesis Imperfecta on Junctional Epithelium Structure and Function. [PDF]

Biology (Basel)
The junctional epithelium, which lines the inner gingival surface, seals the gingival sulcus to block the infiltration of food debris and pathogens. The junctional epithelium is derived from the reduced enamel epithelium, consisting of late developmental
Lin K, Ngu J, Le SU, Zhang Y.
europepmc   +2 more sources

Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regeneration. [PDF]

Int J Oral Sci
Enamel, the hardest mineralized material in the human body, protects the underlying living tissues, the dentin and pulp of the tooth. However, over 90% of adults have lost or damaged enamel and cannot regenerate the protective structure due to lack of ...
Patni AP, Mout R, Alghadeer A, Moore RH, Nademi S, Ausk BJ, Huber P, Keshri R, Regier M, Cornell RA, Gross T, Freedman BS, Daley GQ, Baker D, Mathieu J, Ruohola-Baker H.   +15 more
europepmc   +2 more sources

Impression of the Clock Genes on Oral Health and Diseases: A Narrative Review [PDF]

Journal of Clinical and Diagnostic Research, 2023
The circadian clock helps organisms adapt their physiological processes to changing environmental conditions, including the adaptation of the 24-hour sleep-wake cycle in day and night. Circadian rhythms regulate the proper timing and synchronisation of
Amol Dhokar, Heena Golani, Latisha Prashant Hadkar   +2 more
doaj   +1 more source

Ameloblasts in health and disease

Dentistry and Medical Research, 2021
Ameloblasts are highly sensitive enamel-forming cells. They are derived from ectoderm and undergo a series of transformative changes in their life cycle.
Sandhya Tamgadge, Avinash Tamgadge, Bhagyashree Agre   +2 more
doaj   +1 more source

Na+ and K+ transport and maturation stage ameloblast modulation

Frontiers in Physiology, 2023
Introduction: Enamel mineralization requires calcium transport into the extracellular matrix for the synthesis of hydroxyapatite (HA) crystals. Formation of HA releases protons into the matrix, which are then neutralized when ameloblasts modulate from ...
Jake Ngu, Antonius L. J. J. Bronckers, Kaitlin Katsura, Yan Zhang, Pamela K. Den Besten   +4 more
doaj   +1 more source

Fluorosed mouse ameloblasts have increased SATB1 retention and Gαq activity. [PDF]

PLoS ONE, 2014
Dental fluorosis is characterized by subsurface hypomineralization and increased porosity of enamel, associated with a delay in the removal of enamel matrix proteins.
Yan Zhang, Ji-Yeon Kim, Orapin Horst, Yukiko Nakano, Li Zhu, Ralf J Radlanski, Sunita Ho, Pamela K Den Besten   +7 more
doaj   +1 more source

Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review [PDF]

Journal of Oral Pathology & Medicine, 2017
PurposeTo integrate the available data published to date on ameloblastic fibromas (AF) and ameloblastic fibrosarcomas (AFS) into a comprehensive analysis of their clinical/radiological features.MethodsAn electronic search was undertaken in July 2017.
Chrcanovic, Bruno, Brennan, Peter, Rahimi, Siavash, Santiago Gomez, Ricardo   +3 more
openaire   +4 more sources

Ameloblastic Carcinoma [PDF]

Journal of Maxillofacial and Oral Surgery, 2010
Ameloblastic carcinoma (AC) is a rare aggressive malignant epithelial odontogenic tumor of the maxillofacial skeleton with a distinct predilection in the mandible. It may appear de novo or originate from a pre-existing ameloblastoma or odontogenic cyst. It exhibits cytological features of ameloblastoma and carcinoma.
Hari, Ram, Shadab, Mohammad, Nuzhat, Husain, Prem Narayan, Gupta   +3 more
openaire   +2 more sources

Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes

Frontiers in Cell and Developmental Biology, 2020
Dental epithelial stem cells give rise to four types of dental epithelial cells: inner enamel epithelium (IEE), outer enamel epithelium (OEE), stratum intermedium (SI), and stellate reticulum (SR).
Yuta Chiba, Kan Saito, Daniel Martin, Erich T. Boger, Craig Rhodes, Keigo Yoshizaki, Takashi Nakamura, Aya Yamada, Robert J. Morell, Yoshihiko Yamada, Satoshi Fukumoto, Satoshi Fukumoto   +11 more
doaj   +1 more source