Fluorosed Mouse Ameloblasts Have Increased SATB1 Retention and Gαq Activity [PDF]
PLoS ONE, 2014 Dental fluorosis is characterized by subsurface hypomineralization and increased porosity of enamel, associated with a delay in the removal of enamel matrix proteins.
Yan Zhang, Ji-Yeon Kim
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Immunocytochemical Localization of Claudin-1 in the Maturation Ameloblasts of Rat Incisors
Frontiers in Physiology, 2010 Claudin 1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy.
Sumio Nishikawa, Abe Michio
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Impact of Amelogenesis Imperfecta on Junctional Epithelium Structure and Function [PDF]
BiologyThe junctional epithelium, which lines the inner gingival surface, seals the gingival sulcus to block the infiltration of food debris and pathogens. The junctional epithelium is derived from the reduced enamel epithelium, consisting of late developmental
Kevin Lin +3 more
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Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regeneration [PDF]
International Journal of Oral ScienceEnamel, the hardest mineralized material in the human body, protects the underlying living tissues, the dentin and pulp of the tooth. However, over 90% of adults have lost or damaged enamel and cannot regenerate the protective structure due to lack of ...
Anjali P. Patni +15 more
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The Evolutionary Young Actin Nucleator Cobl Is Important for Proper Amelogenesis [PDF]
CellsThe actin cytoskeleton plays an important role in morphological changes of ameloblasts during the formation of enamel, which is indispensable for teeth to withstand wear, fracture and caries progression.
Hannes Janitzek +7 more
doaj +2 more sources
Small molecules direct the generation of ameloblast-like cells from human embryonic stem cells [PDF]
Stem Cell Research & TherapyBackground Ameloblasts present a promising avenue for the investigation of enamel and tooth regeneration. Previous protocols for directing the differentiation of human embryonic stem cells (hESCs) into dental epithelial (DE) cells involving the need for ...
Ximei Zhu +9 more
doaj +2 more sources
Impression of the Clock Genes on Oral Health and Diseases: A Narrative Review [PDF]
Journal of Clinical and Diagnostic Research, 2023 The circadian clock helps organisms adapt their physiological processes to changing environmental conditions, including the adaptation of the 24-hour sleep-wake cycle in day and night. Circadian rhythms regulate the proper timing and synchronisation of
Amol Dhokar +2 more
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Ameloblasts in health and disease
Dentistry and Medical Research, 2021 Ameloblasts are highly sensitive enamel-forming cells. They are derived from ectoderm and undergo a series of transformative changes in their life cycle.
Sandhya Tamgadge +2 more
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Na+ and K+ transport and maturation stage ameloblast modulation
Frontiers in Physiology, 2023 Introduction: Enamel mineralization requires calcium transport into the extracellular matrix for the synthesis of hydroxyapatite (HA) crystals. Formation of HA releases protons into the matrix, which are then neutralized when ameloblasts modulate from ...
Jake Ngu +4 more
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Calcium Transport in Specialized Dental Epithelia and Its Modulation by Fluoride
Frontiers in Endocrinology, 2021 Most cells use calcium (Ca2+) as a second messenger to convey signals that affect a multitude of biological processes. The ability of Ca2+ to bind to proteins to alter their charge and conformation is essential to achieve its signaling role.
Veronica Costiniti +5 more
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