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Indian Journal of Dental Research, 2011 Odontogenic tumors comprise a complex group of lesions of diverse histopathological types and clinical behavior. The group of mixed odontogenic tumors, which are also rare, is composed of proliferating odontogenic epithelium in a cellular ectomesenchyme resembling dental papilla. Ameloblastic fibrodentinoma is a rare benign odontogenic tumor.
Deepak Bhargava +3 more
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Ameloblastic fibrosarcoma transformation from ameloblastic fibroma
National Journal of Maxillofacial Surgery, 2022 Ameloblastic fibrosarcoma (AFS) is an extremely rare malignant odontogenic tumor. It is composed of benign odontogenic epithelium, resembling that of ameloblastoma, and a mesenchymal part exhibiting features of fibrosarcoma. The development of this lesion in the jaws is either de novo or from preexisting ameloblastic fibroma ...
Ramakrishnan, Divya Sanjeevi +2 more
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Endocytosis and Enamel Formation
Frontiers in Physiology, 2017 Enamel formation requires consecutive stages of development to achieve its characteristic extreme mineral hardness. Mineralization depends on the initial presence then removal of degraded enamel proteins from the matrix via endocytosis.
Cong-Dat Pham +7 more
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Journal of Oral and Maxillofacial Pathology, 2012 Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues. This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation.
Rao, Srinivas Ponnam +2 more
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Ameloblastic fibrodentinosarcoma and ameloblastic fibro-odontosarcoma: A systematic review [PDF]
Journal of Stomatology, Oral and Maxillofacial Surgery, 2018 The purpose of the present review was to integrate the available data published on ameloblastic fibrodentinosarcoma (AFDS) and ameloblastic fibro-odontosarcoma (AFOS) into a comprehensive analysis of their clinical/radiologic features. An electronic search was undertaken in July/2017.
Chrcanovic, Bruno +1 more
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The acid test of fluoride: how pH modulates toxicity. [PDF]
PLoS ONE, 2010 It is not known why the ameloblasts responsible for dental enamel formation are uniquely sensitive to fluoride (F(-)). Herein, we present a novel theory with supporting data to show that the low pH environment of maturating stage ameloblasts enhances ...
Ramaswamy Sharma +4 more
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Cells, 2022 The regulator of calcineurin (RCAN1) has been implicated in the pathogenesis of Down syndrome (DS). Individuals with DS show dental abnormalities for unknown reasons, and RCAN1 levels have been found to be elevated in several tissues of DS patients.
Yi Li +7 more
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Frontiers in Physiology, 2017 Fluorosed maturation stage enamel is hypomineralized in part due to a delay in the removal of matrix proteins to inhibit final crystal growth. The delay in protein removal is likely related to reduced expression of kallikrein-related peptidase 4 (KLK4 ...
Michael H. Le +6 more
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Amelogenesis Imperfecta; Genes, Proteins, and Pathways
Frontiers in Physiology, 2017 Amelogenesis imperfecta (AI) is the name given to a heterogeneous group of conditions characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft, fragile, pitted and/or badly discolored, with poor function and aesthetics,
Claire E. L. Smith +8 more
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Mitochondrial Function in Enamel Development
Frontiers in Physiology, 2020 Enamel is the most calcified tissue in vertebrates. Enamel formation and mineralization is a two-step process that is mediated by ameloblast cells during their secretory and maturation stages.
Veronica Costiniti +9 more
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