Results 41 to 50 of about 3,701 (166)

Targeted overexpression of amelotin disrupts the microstructure of dental enamel. [PDF]

open access: yesPLoS ONE, 2012
We have previously identified amelotin (AMTN) as a novel protein expressed predominantly during the late stages of dental enamel formation, but its role during amelogenesis remains to be determined. In this study we generated transgenic mice that produce
Rodrigo S Lacruz   +8 more
doaj   +1 more source

Tooth histotype and enameloid microstructure of Priohybodus arambourgi d'Erasmo, 1960 (Elasmobranchii: Hybodontiformes) from the Late Jurassic of northeastern Brazil

open access: yesThe Anatomical Record, EarlyView.
Abstract Sharks possess varied diets and different prey capture mechanisms. As a result, the group exhibits a significant diversity in dental morphology, also reflecting the internal structures of the teeth. Internal dental anatomy points to the existence of three histotypes in elasmobranch phylogeny: orthodont, osteodont, and pseudoosteodont ...
Kelly Roberta da Silva   +2 more
wiley   +1 more source

Profiles of Wnt pathway gene expression during tooth morphogenesis

open access: yesFrontiers in Physiology
Mouse and human genetic studies indicate key roles of the Wnt10a ligand in odontogenesis. Previous studies have identified effectors and regulators of the Wnt signaling pathway actively expressed during key stages of tooth morphogenesis.
Resmi Raju   +11 more
doaj   +1 more source

Dental development in the tropical gar (Atractosteus tropicus) and the evolution of vertebrate dentitions

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova   +4 more
wiley   +1 more source

On the pattern of ameloblast migration

open access: yesCell Proliferation, 1989
Abstract The kinetics of ameloblast cells in continuously growing guinea pig molars were studied using autoradiography. The results showed that there was no direct relationship between ameloblast migration rate and ameloblast production rate, which indicated that ameloblasts actively migrated coronally.
Nataatmadja, MI, Orams, HJ, Reade, PC
openaire   +5 more sources

Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin   +4 more
wiley   +1 more source

Epiprofin Transcriptional Activation Promotes Ameloblast Induction From Mouse Induced Pluripotent Stem Cells via the BMP-Smad Signaling Axis

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption.
Xinchao Miao   +11 more
doaj   +1 more source

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang   +3 more
wiley   +1 more source

The Role of Na:K:2Cl Cotransporter 1 (NKCC1/SLC12A2) in Dental Epithelium during Enamel Formation in Mice

open access: yesFrontiers in Physiology, 2017
Na+:K+:2Cl− cotransporters (NKCCs) belong to the SLC12A family of cation-coupled Cl− transporters. We investigated whether enamel-producing mouse ameloblasts express NKCCs.
Rozita Jalali   +10 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen   +8 more
wiley   +1 more source

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