Results 81 to 90 of about 7,940 (198)

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Localised enamel hypoplasia of human deciduous canines: genotype or environment? [PDF]

, 2000
The document attached has been archived with permission from the Australian Dental Association (9th Jan 2008). An external link to the publisher’s copy is included.A discrete area of defective enamel formation that appears on the labial surface of the ...
Brown T., Gedda L., Grothe W., Lukacs JR., Nation WA, Seow WK., Seow WK., Skinner MF, Zahalkova M.   +8 more
core   +1 more source

Amelogenesis Imperfecta caused by N-Terminal Enamelin Point Mutations in Mice and Men is driven by Endoplasmic Reticulum Stress [PDF]

, 2017
‘Amelogenesis imperfecta’ (AI) describes a group of inherited diseases of dental enamel that have major clinical impact. Here, we identify the aetiology driving AI in mice carrying a p.S55I mutation in enamelin; one of the most commonly mutated proteins ...
Alan J. Mighell, Backman, Barron, Bartlett, Betts, Brookes, Brookes, Catriona J. Brown, Cawley, Chan, Chiti, Chris F. Inglehearn, Claire E.L. Smith, Coffield, Cui, Datta, DePristo, Dong, El-Sayed, Ellisdon, Gutierrez, Hart, Helen Rodd, Hetz, Hetz, Hu, Hu, Hu, James A. Poulter, Jennifer Kirkham, Kall, Kang, Kida, Kim, Kim, Lamkanfi, Lindemeyer, Lyngstadaas, Mardh, Martin J. Barron, Masuya, McKenna, Merksamer, Michael J. Dixon, Nanci, Ozcan, Ozdemir, Paediatric Formulary Committee, Parry, Parry, Poulter, Rajpar, Schroder, Sherry, Simmer, Smith, Southwood, Stephanopoulos, Steven J. Brookes   +58 more
core   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Ultrastructural and immunohistochemical study of the influence of fluoride excess on the development of rat incisor tooth buds

Journal of Applied Oral Science, 2007
Little information is available on the pathogenesis of fluorosis during the fetal and initial postnatal period. In the present study, female rats received 0 (control), 7 or 100 ppm of sodium fluoride in drinking water, one week before breeding and ...
Renato Massaharu Hassunuma, Edson Virgílio Zen Filho, Danielle Santi Ceolin, Tania Mary Cestari, Rumio Taga, Gerson Francisco de Assis   +5 more
doaj   +1 more source

Calcium Sets the Clock in Ameloblasts

Frontiers in Physiology, 2020
BackgroundStromal interaction molecule 1 (STIM1) is one of the main components of the store operated Ca2+ entry (SOCE) signaling pathway. Individuals with mutated STIM1 present severely hypomineralized enamel characterized as amelogenesis imperfecta (AI)
Raed Said, Raed Said, Liubov Lobanova, Silvana Papagerakis, Petros Papagerakis, Petros Papagerakis   +5 more
doaj   +1 more source

Overexpression of miR-1306-5p, miR-3195, and miR-3914 Inhibits Ameloblast Differentiation through Suppression of Genes Associated with Human Amelogenesis Imperfecta [PDF]

, 2021
Hiroki Yoshioka, Yin‐Ying Wang, Akiko Suzuki, Meysam Shayegh, Mona Gajera, Zhongming Zhao, Junichi Iwata   +6 more
openalex   +1 more source

Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions

The Anatomical Record, Volume 309, Issue 1, Page 166-186, January 2026.
Abstract This article reviews the pathological changes in the enamel of permanent mandibular cheek teeth and their sequelae in European roe deer from regions polluted by anthropogenic fluoride emissions. The primary (developmental) changes of fluorotic roe deer enamel are hypomineralization and microstructural aberrations, including enamel hypoplasia ...
Uwe Kierdorf, Horst Kierdorf
wiley   +1 more source

Deletion of ameloblastin exon 6 is associated with amelogenesis imperfecta [PDF]

, 2014
Amelogenesis imperfecta (AI) describes a heterogeneous group of inherited dental enamel defects reflecting failure of normal amelogenesis. Ameloblastin (AMBN) is the second most abundant enamel matrix protein expressed during amelogenesis.
Brookes, SJ, Inglehearn, CF, Kirkham, J, Mighell, AJ, Murillo, G, Parry, DA, Poulter, JA, Silva, S, Smith, CEL   +8 more
core   +1 more source

FAM83H Regulates Postnatal T Cell Development Through Thymic Stroma Organization

European Journal of Immunology, Volume 56, Issue 1, January 2026.
Loss of the casein kinase 1 scaffolding protein FAM83H compromises bone marrow lymphopoiesis, reduces Foxn1 expression in cortical thymic epithelial cells (TEC), disrupts thymic architecture and TEC identity, and ultimately impairs double‐negative thymocyte proliferation and T‐cell production.
Betul Melike Ogan, Veronika Forstlova, Laura Jane Dowling, Michaela Simova, Kristina Vicikova, Vendula Novosadova, Frantisek Spoutil, Sylvie Cervenkova, Michaela Procházková, Jolana Tureckova, Olha Fedosieieva, Juraj Labaj, Petr Nickl, Kamila Krizova, Jan Prochazka, Radislav Sedlacek, Jana Balounova   +16 more
wiley   +1 more source