Results 221 to 230 of about 13,126 (251)
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Calcified Tissue International, 1994
Amelogenins were extracted from the thin outer layer of porcine secretory enamel and purified by gel filtration and reverse-phase HPLC. The results of amino acid sequencing of the purified porcine amelogenins indicated the presence of at least four prototype amelogenins translated from alternatively spliced transcripts. The results of mass spectroscopy
Y, Yamakoshi +3 more
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Amelogenins were extracted from the thin outer layer of porcine secretory enamel and purified by gel filtration and reverse-phase HPLC. The results of amino acid sequencing of the purified porcine amelogenins indicated the presence of at least four prototype amelogenins translated from alternatively spliced transcripts. The results of mass spectroscopy
Y, Yamakoshi +3 more
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Probabilistic interpretation of the Amelogenin locus
Forensic Science International: Genetics, 2021We describe a method to assign weights to genotype combinations at the Amelogenin locus. It is a typical practise in forensic laboratories that once the weight exceeds a threshold (such as 99 %), then they can be considered to be resolved enough to interpret (for example to load onto a database).
Jo-Anne Bright +2 more
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Expression of amelogenin in odontoblasts
Bone, 2003Amelogenin is the major enamel protein produced by ameloblasts. Its expression has been shown to be down-regulated in ameloblasts of vitamin-D-deficient (-D) rats. The potential expression and localization of amelogenin in odontoblasts and its regulation by vitamin D were investigated in this study.
P, Papagerakis +5 more
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Quantitative Analysis of Amelogenin Solubility
Journal of Dental Research, 1998Amelogenins are a group of extracellular enamel matrix proteins which are believed to be involved in the regulation of the size and habits of forming enamel crystals. The aim of this study was to compare the solubility properties of several amelogenins at various pH (from 4.0 to 9.0) at constant ionic strength (IS), and to examine the influence of ...
J, Tan +4 more
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The Small Bovine Amelogenin LRAP Fails to Rescue the Amelogenin Null Phenotype
Calcified Tissue International, 2003Amelogenins are the most abundant secreted proteins in developing dental enamel. These evolutionarily-conserved proteins have important roles in enamel mineral formation, as mutations within the amelogenin gene coding region lead to defects in enamel thickness or mineral structure. Because of extensive alternative splicing of the primary RNA transcript
E, Chen +12 more
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Alternative Splicing of Amelogenins
Connective Tissue Research, 1995Amelogenins comprise as much as 90% of the protein in the developing enamel matrix. Separating amelogenins by gel electrophoresis reveals a complex of polypeptides with apparent mobilities ranging from low molecular weight species on up to 28,000 Daltons.
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Journal of Biochemistry, 2008
We previously demonstrated that the uptake of M180 amelogenin protein in dental epithelial cells (HAT-7) results in increased levels of amelogenin mRNA through enhanced mRNA stabilization. To determine the processes involved in the uptake of extracellular M180 amelogenin by cells and in amelogenin intracellular trafficking in the amelogenin protein ...
Liming, Xu +2 more
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We previously demonstrated that the uptake of M180 amelogenin protein in dental epithelial cells (HAT-7) results in increased levels of amelogenin mRNA through enhanced mRNA stabilization. To determine the processes involved in the uptake of extracellular M180 amelogenin by cells and in amelogenin intracellular trafficking in the amelogenin protein ...
Liming, Xu +2 more
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Recent Advances in Amelogenin Biochemistry
Connective Tissue Research, 1995This paper reviews advances in amelogenin biochemistry in three areas; (i) amelogenin expression; (ii) amelogenin post-translational and post-secretory processing, and (iii) amelogenin structure and function. Recent studies of amelogenin expression have demonstrated that alternative-splicing of mouse amelogenin RNA generates seven distinct mRNAs ...
A G, Fincham, J, Moradian-Oldak
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Biochemical and Biophysical Research Communications, 1992
A heterogeneous population of amelogenin proteins is derived from a single copy of the mouse amelogenin gene. To investigate the one gene--multiple protein enigma, we designed a study to distinguish between alternative splicing and proteolytic cleavage models.
E C, Lau +9 more
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A heterogeneous population of amelogenin proteins is derived from a single copy of the mouse amelogenin gene. To investigate the one gene--multiple protein enigma, we designed a study to distinguish between alternative splicing and proteolytic cleavage models.
E C, Lau +9 more
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Hydroxyapatite Growth on Amelogenin‐Amelotin Recombinamers
ChemNanoMat, 2021AbstractStrategies to improve hydroxyapatite mineralization for enamel repair are essential for tissue regeneration. Amelogenin and amelotin (AMTN) are enamel matrix proteins playing critical roles in enamel formation. Amelogenin acts as a scaffold for hydroxyapatite, while AMTN (specifically its ‘SSEEL’ domain) is necessary for proper enamel ...
Dimitra Athanasiadou +5 more
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