Results 51 to 60 of about 15,332 (193)

Defensive medicine in dermatological practice – Dermatopathology as a mirror of structural challenges

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller   +2 more
wiley   +1 more source

Leishmaniose tegumentar americana: apresentação pouco comum American tegumentary leishmaniasis: an unusual presentation

open access: yesAnais Brasileiros de Dermatologia, 2008
Relata-se caso de leishmaniose tegumentar americana com lesões proeminentes na face. Os critérios diagnósticos incluíram dados clínicos e epidemiológicos, intradermorreação de Montenegro, identificação de Leishmania pela reação em cadeia da polimerase e ...
Antonio Carlos Martins Guedes   +2 more
doaj   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

Cutaneous parasitism in patients with American visceral leishmaniasis in an endemic area

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Visceral leishmaniasis (VL) represents a public health concern in several areas of the world. In the American continent, VL transmission is typically zoonotic, but humans with active VL caused by Leishmania infantum are able to infect ...
Carla Riama Lopes de Pádua Moura   +5 more
doaj   +1 more source

Kinetoplastids:related protozoan pathogens, different diseases [PDF]

open access: yes, 2008
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Agranoff   +127 more
core   +4 more sources

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

open access: yesJournal of Microscopy, Volume 301, Issue 2, Page 222-240, February 2026.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson   +2 more
wiley   +1 more source

Analysis of the specificity of human antibodies to antigens of Leishmania braziliensis braziliensis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1989
The antigenicity of promastigotes of Leishmania braziliensis braziliensis (L. b.braziliensis) treated with 1% sodium desoxycholate in 10 mM Tris-Hcl pH 8.2 was analysed by immunoblot using as probes sera from American cutaneous leishmaniasis (ACL ...
Aoi Masuda   +4 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

American cutaneous leishmaniasis in a northeast Brazilian city: clinical and epidemiological features

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION This study characterized the clinico-epidemiological profile of American cutaneous leishmaniasis (ACL) cases in Barbalha, Ceará State, Brazil.
Cícero Roberto Pinheiro Grangeiro Júnior   +11 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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