Macrophage Polarization in the Skin Lesion Caused by Neotropical Species of Leishmania sp
Macrophages play important roles in the innate and acquired immune responses against Leishmania parasites. Depending on the subset and activation status, macrophages may eliminate intracellular parasites; however, these host cells also can offer a safe ...
Carmen M. Sandoval Pacheco +12 more
doaj +1 more source
Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines +7 more
core
Rapid Detection of Leishmania infantum Infection in Dogs: Comparative Study Using an Immunochromatographic Dipstick Test, Enzyme-Linked Immunosorbent Assay, and PCR [PDF]
Current zoonotic visceral leishmaniasis (ZVL) control programs in Brazil include the culling of Leishmania infantum-infected reservoir dogs, a strategy that has failed to prevent a rise of canine and human ZVL cases over the past decade.
Bruce Alex +8 more
core +3 more sources
Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal +3 more
wiley +1 more source
Objective This review aims to identify and evaluate the management options for the extranodal NK/T‐cell lymphoma, nasal type of head and neck in the pediatric population. Methods The study was conducted based on a comprehensive literature review from 2009 to 2025. The following keywords were used: extranodal NK/T cell lymphoma and children and head and
Agata Gierlotka +4 more
wiley +1 more source
Evaluation of a mass distribution programme for fine-mesh impregnated bednets against visceral leishmaniasis in eastern Sudan. [PDF]
During an epidemic of visceral leishmaniasis (VL) in eastern Sudan, Médecins Sans Frontières distributed 357,000 insecticide-treated bednets (ITN) to 155 affected villages between May 1999 and March 2001.
Alten +22 more
core +2 more sources
[American cutaneous leishmaniasis].
American cutaneous leishmaniasis is endemic in widespread areas of Latin America. The causative agents include L. (V.) braziliensis, L. (L.) mexicana, L. (V.) panamensis, and related species. The spectrum of disease includes single, localized, cutaneous ulcers, diffuse cutaneous leishmaniasis, and mucosal disease. The main reservoirs for L.
Bernardo, Gontijo +1 more
openaire +1 more source
Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva +4 more
wiley +1 more source
The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source
Leishmaniasis is a neglected disease that is among the top five endemic infectious and parasitic diseases of major relevance. The aim of this study was to analyze the frequency, the demographic, and epidemiological profile of the patients with ...
Patrícia Pereira Vasconcelos +2 more
doaj +1 more source

