Results 111 to 120 of about 5,175,501 (310)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Stellar feedback effects on the mass distribution of clouds and cloud complexes

open access: yesAstronomy & Astrophysics
Context. Galaxy evolution is sensitive to how stars inject feedback into their surroundings. In particular, the stellar feedback from star clusters strongly affects gas motions and, consequently, the baryonic cycle.
Veroneze Quinalha Luanna   +2 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Natural selection and language genes in humans

open access: yesScientific Reports
In this study we construct lists of candidate genes for articulate language. Analysis of coding regions of over 100 candidate genes for the effects of natural selection (directional episodic selection and relaxed/intensified selection) in the various ...
Rob DeSalle   +6 more
doaj   +1 more source

Historical Macroeconomics and American Macroeconomic History [PDF]

open access: yes
What can macroeconomic history offer macroeconomic theorists and macroeconometricians? Macroeconomic history offers more than longer time series or special `controlled experiments.' It suggests an historical definition of the economy, which has ...
Charles W. Calomiris, Christopher Hanes
core  

Menorah Review (No. 51, Winter, 2001) [PDF]

open access: yes, 2001
Celebrating Nathan Glazer\u27s American Judaism -- Is Process Thought Progress? -- Biblical Claims: The Historical Basis -- Defining and Redefining Jewishness -- Engagement in Writing Jewish History -- Noteworthy ...

core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

The blueprint for survival: the blue dasher dragonfly as a model for urban adaptation

open access: yesBMC Ecology and Evolution
Background Human alteration of natural environments and habitats is a major driver of species decline. However, a handful of species thrive in human altered environments. The biology, distribution, population structure, and molecular adaptations enabling
Ethan R. Tolman   +19 more
doaj   +1 more source

History PhDs in US finding jobs... sort of. What about in Canada? [PDF]

open access: yes, 2020
A new study that was commissioned by the American Historical Association has just been released, and it should be of great interest to historians on both sides of the border. “The Many Careers of History PhDs: A Study of Job Outcomes,” by L.
Talbot, Robert J.
core   +1 more source

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