Results 41 to 50 of about 1,110,699 (292)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Looking for Kunta Kinte: Alex Haley's Roots and African American Genealogies
Iperstoria, 2014 As the 30th anniversary 2006 edition recalls, Alex Haley’s Roots: The Saga of an American Family was a big popular success: in 1976, the year it was published, “the book sold over one million copies” and in 1977 the miniseries created out of it “was ...
Elisa Bordin
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Airborne Toxicity in Don DeLillo’s White Noise
Open Cultural StudiesIn the wake of the COVID-19 pandemic, people across the world came to realize the significant relationship between air and human health. This pandemic, which changed the course of many lives, demonstrated how air serves as a transmitter of viruses ...
Ömerali Uslu Mine
doaj +1 more source
Faulkner's Southern belle - myth or reality?
Acta Neophilologica, 2011 The article deals with heroines of William Faulkner's novels Light in August, Absalom, Absalom!, The Sound and the Fury, The Unvanquished, The Town and his short story "A Rose for Emily". The Southern belle features as a recurring character in Faulkner's
Nataša Intihar Klančar
doaj +1 more source
It is More than a Bunch of Numbers: Trauma, Voicing and Identity in Jennifer Chow’s The 228 Legacy
Res Rhetorica, 2020 This paper explores how Jennifer Chow’s The 228 Legacy (2013) recaptures the buried hi/stories of the 228 Massacre with a trauma narrative about Silk’s deep-kept secrets.
Pi-hua Ni
doaj +1 more source
The Application of Literary Maps to the Teaching of English and American Literature in the Age of Big Data and the Internet of Things [PDF]
, 2022 Chen Binfeng
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source