Results 61 to 70 of about 1,122,224 (262)

Looking for Kunta Kinte: Alex Haley's Roots and African American Genealogies

open access: yesIperstoria, 2014
As the 30th anniversary 2006 edition recalls, Alex Haley’s Roots: The Saga of an American Family was a big popular success: in 1976, the year it was published, “the book sold over one million copies” and in 1977 the miniseries created out of it “was ...
Elisa Bordin
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Introduction to American Literature in the World

open access: yesJournal of Transnational American Studies, 2017
Wai Chee Dimock, introduction to American Literature in the World: An Anthology from Anne Bradstreet to Octavia Butler, ed. Wai Chee Dimock et al. (New York: Columbia University Press, 2017), 1–18.
Wai Chee Dimock
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Remediating the remediated : printed prose in the age of hypertext

open access: yesActa Neophilologica, 2006
The article argues that with the spreading of computer hypertext into the social sphere, hypertext is no longer merely a writing technique or an organising principle; it becomes the logic implicit in the functioning of postmodern  societies.lts ...
Mojca Krevel
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Introduction

open access: yesRSA Journal, 2015
Introduction to the Special Section “American Life and Literature into Film”
Gianfranca Balestra
doaj   +1 more source

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