Results 151 to 160 of about 181,956,994 (291)

Effect of the patient's age on radiotherapy-based adverse effect

, 2012
48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) -- JUN 01-06, 2012 -- Chicago, IL…Amer Soc Clin ...
Akkas, Ebru Atasever, Kacan, Turgut, Babacan, Nalan Akgul, Okur, Yillar, Yucel, Birsen, Eren, Mehmet Fuat, Kilickap, Saadettin   +6 more
core   +1 more source

Pediatric Human Olfactory Epithelium Mirrors Adult Structure and Function in a Human Olfactory Organoid Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Objective This study investigated the developmental differences in structure, gene expression, and function of human olfactory epithelium (OE) using pediatric and adult specimens and human olfactory organoids. Background Olfactory dysfunction (OD) is characterized by loss or alterations in the sense of smell and has an age‐related increase in ...
Randy Bach, Ankit Chauhan, Michael Xiang, Kang‐Hoon Kim, James N. Palmer, Nithin D. Adappa, Michael A. Kohanski, Noam A. Cohen, Hong Wang, Jennifer E. Douglas   +9 more
wiley   +1 more source

Differentiation and Pathological Significance of Tissue‐Resident Memory‐Like CD8+ T Cells in Systemic Lupus Erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Tissue‐resident memory T (TRM) cells have been implicated in organ‐specific immune pathology; however, the pathological relevance of TRM‐like CD8+ T cells in systemic lupus erythematosus (SLE) remains unclear. We investigated their differentiation mechanisms and pathological significance in SLE, including associations with disease activity ...
Yuya Fujita, Kaoru Yamagata, Satoshi Kubo, Ippei Miyagawa, Koshiro Sonomoto, Yurie Satoh‐Kanda, Masanobu Ueno, Shumpei Kosaka, Aya Nawata, Yoshiya Tanaka, Shingo Nakayamada   +10 more
wiley   +1 more source

Patient attitude and survival in advanced non-small cell lung cancer (NSCLC): Results of a prospective observational study.

, 2006
42nd Annual Meeting of the American-Society-of-Clinical-Oncology -- JUN 02-06, 2006 -- Atlanta, GAAmer Soc Clin ...
Chu, D., Altug, S., Reece, W., Hsu, H., Cok, G., Damyanov, D., Park, K., Wang, L., Roubec, J., Patil, S.   +9 more
core  

Increased Risk of Subsequent Cancers in Patients With Sézary Syndrome

American Journal of Hematology, EarlyView.
Julia Nenonen, Despoina Tsakona, Philip Curman, Hanna Brauner   +3 more
wiley   +1 more source

Spatial Proteomics Identifies Distinct Synovial Microenvironments in Hip and Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a heterogeneous joint disease, yet mechanistic insights derive predominantly from knee OA and are often extrapolated to other joints. We investigated joint‐associated differences in the spatial molecular organization of hip and knee OA synovium.
Peng Xie, Antonia R. Sun, Zhengtan Zheng, Yunkun Qu, Feng Gao, Christina Theodoropoulos, Nicholas Matigian, Zhiyong Li, Ross Crawford, Indira Prasadam   +9 more
wiley   +1 more source

Retrospective analysis of 178 patients with stage I rectum cancer.

, 2013
49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) -- MAY 31-JUN 04, 2013 -- Chicago, IL…Amer Soc Clin ...
Seker, Metin, Turan, Nedim, Aksoy, Sercan, Demirci, Umut, Yazilitas, Dogan, Ozdemir, Nuriye, Colak, Dilsen, Ozturk, Banu, Dane, Faysal, Yuksel, Sinemis, Kucukoner, Mehmet, Taskoylu, Burcu, Aksahin, Arzu, Durnali, Ayse, Cihan, Sener, Atasoy, Ajlan, Urakci, Zuhat   +16 more
core   +1 more source

Randomized phase 3 trial of irinotecan (CPT-11)+5FU/folinic acid (FA) vs CDDP+5FU in 1(st)-line advanced gastric cancer patients

, 2005
41st Annual Meeting of the American-Society-of-Clinical-Oncology -- MAY 13-17, 2005 -- Orlando, FLAmer Soc Clin ...
Goker, E, Bugat, R, Dank, M, Risse, ML, Awad, L, Valvere, V, Peschel, C, Wenczl, M, Zaluski, J, Barone, C   +9 more
core  

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source