Results 191 to 200 of about 181,956,994 (291)

Beyond BMI: Unsupervised Machine Learning Clustering of Bioelectrical Impedance Phenotypes Is Associated With Weight‐Recovery Trajectories in Anorexia Nervosa

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To identify data‐driven body composition phenotypes in patients with moderate‐to‐extreme anorexia nervosa (AN) using machine learning (ML) clustering of bioelectrical impedance analysis (BIA) parameters, and to test whether these phenotypes have specific psychopathological and childhood trauma profiles while correlating with early ...
Emanuele Cassioli   +12 more
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo   +10 more
wiley   +1 more source

Seeking American Society of Clinical Oncology-Quality Oncology Practice Initiative (ASCO-QOPI) certification in a northern New England rural health system and cancer care network. [PDF]

open access: yesLearn Health Syst
Perrey HM   +18 more
europepmc   +1 more source

Prepare, don't scare: Rethinking cognitive readiness before epilepsy surgery

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy surgery is an effective but underutilized treatment for drug‐resistant epilepsy, and concerns about postsurgical cognitive change are a prominent barrier. Refinements in surgical technique can reduce cognitive impact, but cognitive change cannot always be avoided, and approaches carrying lower cognitive risk are often less effective ...
Kayela Arrotta   +3 more
wiley   +1 more source

Autonomous Nanomedicine: Closing the Biological Validation Gap

open access: yesExploration, EarlyView.
Delivery of nanoparticles to tumors has not improved in over fifteen years, and biological testing remains slow and separate from formulation design. This review proposes adding a Biology step to the design cycle, using organ chips and patient‐derived organoids, and assesses the readiness of each required technology.
Yan Jun Lin, Izabella Komperda
wiley   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

open access: yesFlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu   +3 more
wiley   +1 more source

From Nodal Metastasis to Oncologic Recurrence in Tongue and Oral Floor Squamous Cell Carcinoma: Distinct Failure Patterns and Clinicopathological Risk Profiles

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau   +9 more
wiley   +1 more source

A Discharge Summary Prompt Reduces Postoperative Radiotherapy Delay in Head and Neck Cancer Patients

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Delays in postoperative radiotherapy (PORT) beyond 6 weeks are associated with worse outcomes in head and neck cancer (HNC). This study evaluated whether a discharge summary prompt could reduce PORT delay. Methods A retrospective review of patients from 2018 to 2023 was used as a pre‐intervention baseline.
Andreja Radevic   +10 more
wiley   +1 more source

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