Results 221 to 230 of about 181,956,994 (291)

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka   +9 more
wiley   +1 more source

Cancer in Seychelles: A Population‐Based Study on Incidence, Trends and Stage at Diagnosis (2005–2024)

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Seychelles, the smallest country in Africa but with the highest GDP per capita, has experienced rapid socioeconomic development. We analysed 20‐year cancer incidence trends (2005–2024) using data from the Seychelles National Cancer Registry (SNCR).
Anne Finesse   +5 more
wiley   +1 more source

Outcomes Following Pancreatoduodenectomy With Arterial Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes to Venous or no Vascular Resection Over 5 Years

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evaluation of arterial resection (AR) during pancreatoduodenectomy (PD) remains limited. This study compares PD with AR to PD with venous resection (VR) and no vascular resection (NVR). Patient demographics, outcomes, and changes over 5 years are evaluated.
Kevin Verhoeff   +7 more
wiley   +1 more source

Is Ductal Carcinoma In Situ a Precursor or Low‐Risk Variant of Invasive Breast Cancer? A Population Perspective

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Ductal carcinoma in situ (DCIS) is usually detected with mammography screening and assumed to be a precursor of invasive ductal cancer (IDC) of the breast. Yet, despite an approximately 10‐fold increase in the rate of DCIS detection and treatment within 20 years following implementation of mammography screening in the United States, IDC ...
Ismail Jatoi   +4 more
wiley   +1 more source

Lymphovascular space involvement as a prognostic factor for survival outcomes in vulvar cancer: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Lymphovascular space involvement (LVSI) is a significant prognostic factor of survival outcomes in gynecologic oncology. Synthetic studies on vulvar cancer are lacking as well as clear consensus about the importance of LSVI in vulvar cancer.
Vasilios Pergialiotis   +6 more
wiley   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer   +20 more
wiley   +1 more source

Asia‐enriched survey of spatial biology and three‐dimensional pathology

open access: yesiMeta, EarlyView.
An Asia‐enriched survey of 239 respondents found that reported implementation of spatial biology and three‐dimensional pathology varied across self‐rated experience groups. Respondents identified cost, analytical complexity, limited standardization, and insufficient interdisciplinary expertise as barriers, highlighting the needs for practical workflows
Zhengyang Wang   +33 more
wiley   +1 more source

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