Results 191 to 200 of about 339,266 (327)

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Development and validation of an advanced low-order panel method [PDF]

A low-order potential-flow panel code, PMARC, for modeling complex three-dimensional geometries, is currently being developed at NASA Ames Research Center. The PMARC code was derived from a code named VSAERO that was developed for Ames Research Center by
Ashby, Dale L., Dudley, Michael, Iguchi, Steven K.   +2 more
core   +1 more source

Resolution of historically discordant Ames test negative/rodent carcinogenicity positive N-nitrosamines using a sensitive, OECD-aligned design. [PDF]

Mutagenesis
Thomas DN, Wills JW, Burman M, Williams AN, Harte DSG, Buckley RA, Urquhart MW, Bretonnet AS, Jeffries B, White AT, Harvey JS, Howe JR, Lynch AM.   +12 more
europepmc   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

A new design concept for indraft wind-tunnel inlets with application to the national full-scale aerodynamic complex [PDF]

The present inlet design concept for an indraft wind tunnel, which is especially suited to applications for which a specific test section flow quality is required with minimum inlet size, employs a cascade or vaneset to control flow at the inlet plane ...
Meyn, Larry A., Olson, Lawrence E., Ross, James C., Vanaken, Johannes M.   +3 more
core   +1 more source

Within-laboratory reproducibility of Ames test results: Are repeat tests necessary? [PDF]

Environ Mol Mutagen
Zeiger E, Mitchell CA, Pfuhler S, Liao Y, Witt KL.   +4 more
europepmc   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source

Quantitative Electron Beam‐Single Atom Interactions Enabled by Sub‐20‐pm Precision Targeting

Advanced Science, EarlyView.
Atomic lock‐on (ALO) is a rapid, low‐dose in situ technique in scanning transmission electron microscopy (STEM) that achieves sub‐20 picometer (pm) beam positioning. A sparse annular scan collects positional information while avoiding irradiation of the target site.
Kevin M. Roccapriore, Frances M. Ross, Julian Klein   +2 more
wiley   +1 more source

Aircraft flight flutter testing at the NASA Ames-Dryden Flight Research Facility [PDF]

Many parameter identification techniques have been used at the NASA Ames Research Center, Dryden Research Facility at Edwards Air Force Base to determine the aeroelastic stability of new and modified research vehicles in flight.
Kehoe, Michael W.
core   +1 more source

Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters. [PDF]

Mutagenesis
Thomas DN, Wills JW, Tracey H, Baldwin SJ, Burman M, Williams AN, Harte DSG, Buckley RA, Lynch AM.   +8 more
europepmc   +1 more source