Results 191 to 200 of about 339,266 (327)

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu   +10 more
wiley   +1 more source

Development and validation of an advanced low-order panel method [PDF]

open access: yes
A low-order potential-flow panel code, PMARC, for modeling complex three-dimensional geometries, is currently being developed at NASA Ames Research Center. The PMARC code was derived from a code named VSAERO that was developed for Ames Research Center by
Ashby, Dale L.   +2 more
core   +1 more source

Resolution of historically discordant Ames test negative/rodent carcinogenicity positive N-nitrosamines using a sensitive, OECD-aligned design. [PDF]

open access: yesMutagenesis
Thomas DN   +12 more
europepmc   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei   +11 more
wiley   +1 more source

A new design concept for indraft wind-tunnel inlets with application to the national full-scale aerodynamic complex [PDF]

open access: yes
The present inlet design concept for an indraft wind tunnel, which is especially suited to applications for which a specific test section flow quality is required with minimum inlet size, employs a cascade or vaneset to control flow at the inlet plane ...
Meyn, Larry A.   +3 more
core   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

open access: yesAdvanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li   +17 more
wiley   +1 more source

Quantitative Electron Beam‐Single Atom Interactions Enabled by Sub‐20‐pm Precision Targeting

open access: yesAdvanced Science, EarlyView.
Atomic lock‐on (ALO) is a rapid, low‐dose in situ technique in scanning transmission electron microscopy (STEM) that achieves sub‐20 picometer (pm) beam positioning. A sparse annular scan collects positional information while avoiding irradiation of the target site.
Kevin M. Roccapriore   +2 more
wiley   +1 more source

Aircraft flight flutter testing at the NASA Ames-Dryden Flight Research Facility [PDF]

open access: yes
Many parameter identification techniques have been used at the NASA Ames Research Center, Dryden Research Facility at Edwards Air Force Base to determine the aeroelastic stability of new and modified research vehicles in flight.
Kehoe, Michael W.
core   +1 more source

Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters. [PDF]

open access: yesMutagenesis
Thomas DN   +8 more
europepmc   +1 more source

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