Results 291 to 300 of about 339,266 (327)

The Salmonella (Ames) Test for Mutagenicity

Current Protocols in Toxicology, 1999
AbstractThe Ames test is a widely accepted short‐term assay for detecting chemicals that induce mutations in the DNA of organisms. The assay is a reverse mutation assay that detects the mutational reversion of his‐dependent Salmonella to his‐independent colonies.
Kristien Mortelmans, Errol Zeiger
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Funktionale Tests am Demonstrator

2020
Zur Validierung der integrierten Funktionen wurden funktionale Tests an Komponenten des LeiFu-Unterbodens durchgefuhrt. Hierbei wurden exemplarisch das Crashverhalten, das NVH-Verhalten, die thermische Isolation bzw. Abstrahlung sowie integrierte elektrische als auch sensorische Funktionen experimentell validiert. Des Weiteren erfolgt in Kap.
Maximilian Hardt, Klaus Fürderer, Peter Middendorf   +2 more
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Mutagenicity of Glutathione and Cysteine in the Ames Test

Science, 1983
Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine independence. Glutathione was also activated by kidney postmitochondrial supernatant but not by liver preparations.
Miroslava Protić-Sabljić, Franz Oesch, Hansruedi Glatt   +2 more
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Use of the Ames test in toxicology

Regulatory Toxicology and Pharmacology, 1985
The Salmonella/microsome assay (Ames test) is one of the most widely used short-term tests. Despite the ubiquitous presence of this assay and the large number of chemicals tested, there is still controversy over the value of Salmonella/microsome assay results in risk assessment.
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Comparative Ames-test study with dyes

Mutation Research/Environmental Mutagenesis and Related Subjects, 1982
I Institut fi~r Toxikologie, Bayer A G, Postfaeh 101709, D-5600 Wuppertal 1 (F.R.G.)," 2 Ciba-Geigy A G, R 1034.2.01, Postfaeh, CH-4002 Basle (Switzerland); 3 lnstitutfiir Gewerbehygiene und Toxikologie, BASF A G, Postfach, D-6700 Ludwigshafen (F.R.G.)," 4 Hoechst A G, Postfach 800320, D-6230 Frankfurt 80 (F.R.G.); and 5 Central Toxicological ...
D. Gericke, P. Arni, B.A. Herbold, E. Longstaff, G. Engelhardt   +4 more
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Regression analysis of ames test data

Environmental Mutagenesis, 1981
AbstractWeighted least squares estimation is used for fitting nonlinear models to Ames test data. The models are biologically plausible, incorporating mutagenicity, toxicity, and/or saturation. Regressions are weighted to compensate for variance that changes with mean and to attain outlier resistance.
Thomas J. Wolff, Nancy H. Sexton, Lawrence Myers, Leslie I. Southerland   +3 more
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The mutagenicity of some edible mushrooms in the Ames test

Food and Cosmetics Toxicology, 1982
The mutagenic activity of five wild and two cultivated species of edible mushrooms was studied in the Ames Salmonella/microsome test system. The wild mushrooms tested were four species of the genus Lactarius (L. necator, L. torminosus, L. helvus and L. rufus) and bolete (Boletus edulis).
A, von Wright, J, Knuutinen, S, Lindroth, M, Pellinen, K G, Widén, E L, Seppä   +5 more
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Biostatistics of Ames-Test Data

1980
In 1976, Matter stated with regard to the problem of interpreting mutagenicity test results: “Although most environmental compounds can be expected to produce either negative or ‘weak’ effects, there seems to be no scientific work available today that deals with the statistical handling of such results.
K. Norpoth, A. Reisch, A. Heinecke
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Ames testing of direct black 38 parallels carcinogenicity testing

Journal of Applied Toxicology, 1981
AbstractStudies have established that Direct Black 38 and two other benzidine‐based dyes are carcinogenic. The carcinogenic effect has been generally considered attributable to the metabolic release of benzidine from Direct Black 38 and similar dyes. However, Ames tests indicated that when Direct Black 38 is reduced with sodium dithionate it is more ...
John A. Elliott, Arthur R. Gregory, Paul Kluge   +2 more
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Mutagenicity of white grape juice in the ames test

Food and Chemical Toxicology, 1996
The mutagenicity of commercially available white grape juice was evaluated in the Ames mutagenicity test. Grape juice elicited a positive mutagenic, response in Salmonella typhimurium strain TA104 and a weaker response in strains TA97, TA98, TA100 and TA1530.
Patrineli, A, Clifford, MN, Walker, R, Ioannides, C   +3 more
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