Results 41 to 50 of about 2,292 (156)
, 2022 A transgenic mouse approach using bacterial artificial chromosomes (BAC) was used to identify regulatory regions that direct Müllerian duct expression for Amhr2 and Osterix (Osx, also known as Sp7). Amhr2 encodes the receptor that mediates anti-Müllerian
Soazik P. Jamin (13945791) +5 more
core +1 more source
Differences in Gynecologic Tumor Development in Amhr2-Cre Mice With KRASG12D or KRASG12V Mutations [PDF]
, 2020 How different KRAS variants impact tumor initiation and progression in vivo has not been thoroughly examined. We hypothesize that the ability of either KRASG12D or KRASG12V mutations to initiate tumor formation is context dependent.
Kun, Eucharist H S +8 more
core +1 more source
Molecular Mechanisms of AMH Signaling
Frontiers in Endocrinology, 2022 Anti-Müllerian Hormone (AMH) is a secreted glycoprotein hormone with critical roles in reproductive development and regulation. Its chemical and mechanistic similarities to members of the Transforming Growth Factor β (TGF-β) family have led to its ...
James A. Howard +2 more
doaj +1 more source
Wilms' Tumor Protein Wt1 Is an Activator of the Anti-Müllerian Hormone Receptor Gene Amhr2
, 2009 The Wilms' tumor protein Wt1 plays an essential role in mammalian urogenital development. WT1 mutations in humans lead to a variety of disorders, including Wilms' tumor, a pediatric kidney cancer, as well as Frasier and Denys-Drash syndromes.
Besenbeck, Birgit +4 more
core +1 more source
Animals, 2022 Anti-Müllerian hormone (AMH) is secreted by the ovaries of female animals and exerts its biological effects through the type II receptor (AMHR2). AMH regulates follicular growth by inhibiting the recruitment of primordial follicles and reducing the ...
Xue Yu +8 more
doaj +1 more source
, 2022 Persistent Müllerian duct syndrome (PMDS) is a rare autosomal recessive disorder of sexual development in males, defined by the presence of Müllerian remnants with otherwise normal sexual differentiation.
Ruzhu Lan, Yang Liu, Sida Wang, Jun Yang
core +1 more source
A Novel Mutation of AMHR2 in Two Siblings with Persistent Müllerian Duct Syndrome [PDF]
, 2018 Persistent Müllerian Duct syndrome (PMDS) develops due to deficiency of anti-Müllerian hormone (AMH) or insensitivity of target organs to AMH in individuals with 46,XY karyotype.
Onay H. +5 more
core +2 more sources
Advanced Science, EarlyView.Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
Network Pharmacology and In Vivo Validation Reveal Therapeutic Effects of Sutaehwan in Polycystic Ovary Syndrome by Modulating AMH-AMHR2 Signaling Pathway. [PDF]
Reprod SciThis study aimed to investigate the therapeutic effects and underlying mechanisms of Sutaehwan (STH), a traditional herbal formula, in polycystic ovary syndrome (PCOS), with a focus on anti-M\ufcllerian hormone (AMH)-driven ovarian dysfunction. A network
Choi Y +5 more
europepmc +2 more sources
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source