Results 21 to 30 of about 2,292 (156)

Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis

Cell Reports, 2023
Summary: Cancer-associated mesothelial cells (CAMCs) in the tumor microenvironment are thought to promote growth and immune evasion. We find that, in mouse and human ovarian tumors, cancer cells express anti-Müllerian hormone (AMH) while CAMCs express ...
M. Chauvin, M.-C. Meinsohn, S. Dasari, P. May, S. Iyer, N.M.P. Nguyen, E. Oliva, Z. Lucchini, N. Nagykery, A. Kashiwagi, R. Mishra, R. Maser, J. Wells, C.J. Bult, A.K. Mitra, Patricia K. Donahoe, D. Pépin   +16 more
doaj   +1 more source

Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity

Middle East Fertility Society Journal, 2022
Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for ...
Fateme Montazeri, Seyed Mehdi Kalantar, Farzaneh Fesahat, Mohammad Hasan Sheikhha, Marjan Omidi, Hanieh Shafienia, Seyed Mehdi Hoseini   +6 more
doaj   +1 more source

Prevalence of the AMHR2 mutation in Miniature Schnauzers and genetic investigation of a Belgian Malinois with persistent Müllerian duct syndrome [PDF]

, 2018
Persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Important consequences of PMDS are cryptorchidism and its sequelae of infertility and increased risk of testicular ...
dCSCA RMSC-1, Leerstoel Dijkerman, Ekenstedt, K J, Furrow, E., dCSCA AVR, Lim, C K, Onderzoek, Smit, M M, Minor, K M, Leegwater, Peter   +9 more
core   +2 more sources

Recombinant anti-Müllerian hormone in the maturation medium improves the in vitro maturation of human immature (GV) oocytes after controlled ovarian hormonal stimulation

Reproductive Biology and Endocrinology, 2022
Background In vitro maturation (IVM) of oocytes is a laboratory method that allows the maturation of immature (GV) oocytes retrieved from patients enrolled in the in vitro fertilization (IVF) programme.
Jure Bedenk, Tadeja Režen, Taja Železnik Ramuta, Nina Jančar, Eda Vrtačnik Bokal, Ksenija Geršak, Irma Virant Klun   +6 more
doaj   +1 more source

A novel mutation of AMHR2 in two brothers with persistent Müllerian duct syndrome and their intracytoplasmic sperm injection outcome

Molecular Genetics & Genomic Medicine, 2021
Background Persistent Müllerian duct syndrome (PMDS) is defined as the presence of Müllerian duct derivatives in an otherwise normally virilized 46, XY male.
Jianzheng Fang, Gao Gao, Jinyong Liu, Lingbo Cai, Yugui Cui, Xiaoyu Yang   +5 more
doaj   +1 more source

Involvement of Transforming Growth Factor Beta Family Genes in Gonadal Differentiation in Japanese Eel, Anguilla japonica, According to Sex-Related Gene Expressions

Cells, 2021
The gonochoristic feature with environmental sex determination that occurs during the yellow stage in the eel provides an interesting model to investigate the mechanisms of gonadal development.
Chien-Ju Lin, Shan-Ru Jeng, Zhen-Yuan Lei, Wen-Shiun Yueh, Sylvie Dufour, Guan-Chung Wu, Ching-Fong Chang   +6 more
doaj   +1 more source

AMH and AMHR2 Involvement in Congenital Disorders of Sex Development [PDF]

, 2021
Anti-Müllerian hormone (AMH) is one of the two testicular hormones involved in male development of the genitalia during fetal life. When the testes differentiate, AMH is secreted by Sertoli cells and binds to its specific receptor type II (AMHR2) on the ...
Brunello, Franco Gino, Rey, Rodolfo Alberto   +1 more
core   +1 more source

A Y-linked anti-Müllerian hormone type-II receptor is the sex-determining gene in ayu, Plecoglossus altivelis.

PLoS Genetics, 2021
Whole-genome duplication and genome compaction are thought to have played important roles in teleost fish evolution. Ayu (or sweetfish), Plecoglossus altivelis, belongs to the superorder Stomiati, order Osmeriformes.
Masatoshi Nakamoto, Tsubasa Uchino, Eriko Koshimizu, Yudai Kuchiishi, Ryota Sekiguchi, Liu Wang, Ryusuke Sudo, Masato Endo, Yann Guiguen, Manfred Schartl, John H Postlethwait, Takashi Sakamoto   +11 more
doaj   +1 more source

CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4. [PDF]

PLoS ONE, 2012
Constitutive activation of the WNT signaling effector CTNNB1 (β-catenin) in the Sertoli cells of the Ctnnb1(tm1Mmt/+);Amhr2(tm3(cre)Bhr/+) mouse model results in progressive germ cell loss and sterility.
Alexandre Boyer, Jonathan R Yeh, Xiangfan Zhang, Marilène Paquet, Aurore Gaudin, Makoto C Nagano, Derek Boerboom   +6 more
doaj   +1 more source

Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer

Cell Reports, 2016
Anti-Müllerian hormone (AMH) and its type II receptor AMHR2, both previously thought to primarily function in gonadal tissue, were unexpectedly identified as potent regulators of transforming growth factor (TGF-β)/bone morphogenetic protein (BMP ...
Tim N. Beck, Vladislav A. Korobeynikov, Alexander E. Kudinov, Rachel Georgopoulos, Nehal R. Solanki, Magda Andrews-Hoke, Timothy M. Kistner, David Pépin, Patricia K. Donahoe, Emmanuelle Nicolas, Margret B. Einarson, Yan Zhou, Yanis Boumber, David A. Proia, Ilya G. Serebriiskii, Erica A. Golemis   +15 more
doaj   +1 more source