Results 11 to 20 of about 2,292 (156)

Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosome system [PDF]

Cell Communication and Signaling
Sex determination mechanisms vary significantly across different chromosomal systems and evolutionary contexts. Nonetheless, the regulatory framework governing the multi-sex chromosome system (X1X1X2X2/X1X2Y) remains enigmatic.
Haixia Zhao, Jun Li, Zhizhong Xiao, Yongshuang Xiao   +3 more
doaj   +3 more sources

AMH and AMHR2 Polymorphisms and AMH Serum Level Can Predict Assisted Reproduction Outcomes: A Cross-Sectional Study

Cellular Physiology and Biochemistry, 2015
Background: In human assisted reproduction, the ovarian response to exogenous recombinant Follicle-stimulating Hormone (FSH) therapy is variable and difficult to predict.
Carla Peluso, Fernando L.A. Fonseca, Guilherme G. Gastaldo, Denise M. Christofolini, Emerson Barchi Cordts, Caio P. Barbosa, Bianca Bianco   +6 more
doaj   +2 more sources

A transgenic bacterial artificial chromosome approach to identify regulatory regions that direct Amhr2 and Osterix expression in Müllerian duct mesenchyme [PDF]

Frontiers in Cell and Developmental Biology, 2022
A transgenic mouse approach using bacterial artificial chromosomes (BAC) was used to identify regulatory regions that direct Müllerian duct expression for Amhr2 and Osterix (Osx, also known as Sp7). Amhr2 encodes the receptor that mediates anti-Müllerian
Malcolm M. Moses, Malcolm M. Moses, Rachel D. Mullen, Daniel I. Idowu, Peter Maye, Soazik P. Jamin, Soazik P. Jamin, Richard R. Behringer, Richard R. Behringer   +8 more
doaj   +2 more sources

Oocyte-cumulus cell interaction: a key factor in early embryo development. [PDF]

Biol Rev Camb Philos Soc
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Torres-Garrido M, Yeste M, Mateo-Otero Y.   +2 more
europepmc   +2 more sources

Interactions between genetic variants in AMH and AMHR2 may modify age at natural menopause. [PDF]

PLoS ONE, 2013
The onset of menopause has important implications on women's fertility and health. We previously identified genetic variants in genes involved in initial follicle recruitment as potential modifiers of age at natural menopause. The objective of this study
Marieke G M Braem, Marlies Voorhuis, Yvonne T van der Schouw, Petra H M Peeters, Leo J Schouten, Marinus J C Eijkemans, Frank J Broekmans, N Charlotte Onland-Moret   +7 more
doaj   +2 more sources

Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes. [PDF]

Mol Ecol
ABSTRACT Sex chromosomes have evolved repeatedly across eukaryotes. The emergence of a sex‐determining (SD) locus is expected to progressively restrict recombination, driving convergent molecular differentiation. However, evidence from taxa like teleost fishes, representing over half of vertebrate species with unmatched diversity in SD systems ...
Hospodářská M, Mora P, Voleníková AC, Al-Rikabi A, Altmanová M, Simanovsky SA, Tolar N, Pavlica T, Janečková K, Štundlová J, Bobryshava K, Jankásek M, Hiřman M, Liehr T, Reichard M, Krysanov EY, Ráb P, Englert C, Nguyen P, Sember A.   +19 more
europepmc   +2 more sources

Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II [PDF]

Journal of Immunology Research, 2015
Anti-Müllerian hormone receptor, type II (AMHR2), is a differentiation protein expressed in 90% of primary epithelial ovarian carcinomas (EOCs), the most deadly gynecologic malignancy.
Cagri Sakalar, Suparna Mazumder, Justin M. Johnson, Cengiz Z. Altuntas, Ritika Jaini, Robert Aguilar, Sathyamangla V. Naga Prasad, Denise C. Connolly, Vincent K. Tuohy   +8 more
doaj   +2 more sources

Can polymorphisms of AMH/AMHR2 affect ovarian stimulation outcomes? A systematic review and meta-analysis

Journal of Ovarian Research, 2020
Background Previous studies have investigated the effects of anti-Müllerian hormone (AMH) and AMH type II receptor (AMHR2) polymorphisms on ovarian stimulation outcomes, but the results were inconsistent.
Di Chen, Xiangyu Zhu, Jielei Wu
doaj   +2 more sources

PCOS Influences the Expression of AMHRII in the Endometrium of AEH During the Reproductive Age [PDF]

Diagnostics
Background: Endometrial proliferative lesions (EPLs) encompass endometrial hyperplasia (EH) and endometrial carcinoma (EC). Atypical endometrial hyperplasia (AEH) is associated with an elevated risk of progression to EC.
Yingsha Yao, Shulan Zhu, Xiaoming Zhu
doaj   +2 more sources

Persistent Müllerian Duct Syndrome with Supernumerary Testicles Due to a Novel Homozygous Variant in the AMHR2 Gene and Literature Review

Diagnostics
Introduction: Persistent Müllerian duct syndrome (PMDS) is a rare disorder of sex development (DSD) caused by mutations in the genes coding anti-Müllerian hormone (AMH) or the AMH receptor, characterized by the persistence of Müllerian derivatives, the ...
Luminita Nicoleta Cima, Iustina Grosu, Isabela Magdalena Draghici, Augustina Cornelia Enculescu, Adela Chirita-Emandi, Nicoleta Andreescu, Maria Puiu, Carmen Gabriela Barbu, Simona Fica   +8 more
doaj   +2 more sources