Results 1 to 10 of about 618,010 (298)

Two-Dimensional Infrared Spectroscopy of Antiparallel β-Sheet Secondary Structure [PDF]

, 2004
We investigate the sensitivity of femtosecond Fourier transform two-dimensional infrared spectroscopy to protein secondary structure with a study of antiparallel β-sheets.
Barth A., Byler D. M., Chatani E., Cheatum C. M., Chirgadze Y. N., Choi J. H., Demirdöven N., Demirdöven N., Dyer R. B., Elliott A., Gerber R. B., Golonzka O., Golonzka O., Ham S., Hamm P., Hamm P., Haris P. I., Hochstrasser R. M., Hybl J. D., Jackson M., Keiderling T. A., Khalil M., Khalil M., Khalil M., Krimm S., Krimm S., Kubelka J., Miyazawa T., Miyazawa T., Oliveira K. M., Rypniewski W. R., Salemme F. R., Searle M. S., Stanger H. E., Surewicz W. K., Susi H., Tokmakoff A., Torii H., Torii H., Torii H., Weisgerber S., Williams R. B., Woutersen S., Woutersen S., Woutersen S., Woutersen S., Zanni M. T., Zanni M. T.   +47 more
core   +21 more sources

New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2

Molecules, 2021
A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (TDP1) and 2 (TDP2) enzymes.
Oksana V. Salomatina, Nadezhda S. Dyrkheeva, Irina I. Popadyuk, Alexandra L. Zakharenko, Ekaterina S. Ilina, Nina I. Komarova, Jóhannes Reynisson, Nariman F. Salakhutdinov, Olga I. Lavrik, Konstantin P. Volcho   +9 more
doaj   +1 more source

Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety

Frontiers in Chemistry, 2022
Twenty-three novel trifluoromethyl pyrimidine derivatives containing an amide moiety were designed and synthesized through four-step reactions and evaluated for their antifungal, insecticidal, and anticancer properties.
Wenjun Lan, Xuemei Tang, Jia Yu, Qiang Fei, Wenneng Wu, Pei Li, Heng Luo   +6 more
doaj   +1 more source

Amide nitrogen pyramidalization changes lactam amide spinning [PDF]

Nature Communications, 2019
AbstractAlthough cis-trans lactam amide rotation is fundamentally important, it has been little studied, except for a report on peptide-based lactams. Here, we find a consistent relationship between the lactam amide cis/trans ratios and the rotation rates between the trans and cis lactam amides upon the lactam chain length of the stapling side-chain of
Yuko Otani, Xin Liu, Hisashi Ohno, Siyuan Wang, Luhan Zhai, Aoze Su, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada   +8 more
openaire   +3 more sources

An amide cyclophane [PDF]

Acta Crystallographica Section E Structure Reports Online, 2014
The title compound, 8,18-dithia-2,6-diaza-13(1,4)-piperidina-1(1,2),4(1,3),7(1,2)-tribenzenaoctadecaphane-10,15-diyne-3,6-dione, C32H30N4O2S2, is composed of a relatively planar bis(2-mercaptophenyl)isophthalamide unit linked to a bridging 1,4-di(but-2-yn-1-yl)piperazine unit, forming a macrocycle.
Vijayan Viswanathan, Ayyavu Thirunarayanan, Perumal Rajakumar, Devadasan Velmurugan   +3 more
openaire   +3 more sources

Synthesis and Estimation of the Insecticide and Antibacterial Activities for Some New Amide Derivatives

Indonesian Journal of Chemistry, 2023
In this work, new compounds of amide derivatives (C1-C3) were synthesized through the conversion reaction of p-chloroaniline to diazonium salt (B1), which reacts with aniline to form a new azo-compound (B3).
Zinah Hussein Ali, Dina Saleem, Abbas Khudhair Abbas, Baneen Salam Rasool, Mustafa Sabri Cheyad   +4 more
doaj   +1 more source

Synthesis and RP-TLC lipophilicity evaluation of a novel fluocinolon acetonide soft drug derivative [PDF]

Kragujevac Journal of Science, 2016
Cortienic acid was obtained by periodic acid oxidation of fluocinolone acetonide, whereas corresponding amide was synthesized from the cortienic acid and ethyl ester of b-alanine by dicyclohexylcarbodiimide - hydroxybenzotriazole coupling procedure ...
Dobričić Vladimir, Vladimirov Sote, Čudina Olivera   +2 more
doaj   +1 more source

Synthesis of Functionalized N-(4-Bromophenyl)furan-2-carboxamides via Suzuki-Miyaura Cross-Coupling: Anti-Bacterial Activities against Clinically Isolated Drug Resistant A. baumannii, K. pneumoniae, E. cloacae and MRSA and Its Validation via a Computational Approach

Pharmaceuticals, 2022
N-(4-bromophenyl)furan-2-carboxamide (3) was synthesized by the reaction furan-2-carbonyl chloride (1) and 4-bromoaniline (2) in the presence of Et3N in excellent yields of 94%.
Ayesha Siddiqa, Muhammad Zubair, Muhammad Bilal, Nasir Rasool, Muhammad Usman Qamar, Aqsa Khalid, Gulraiz Ahmad, Muhammad Imran, Sajid Mahmood, Ghulam Abbas Ashraf   +9 more
doaj   +1 more source

Progress in C-C and C-Heteroatom Bonds Construction Using Alcohols as Acyl Precursors

Molecules, 2022
Acyl moiety is a common structural unit in organic molecules, thus acylation methods have been widely explored to construct various functional compounds.
Feng Zhao, Bin Tan, Qing Li, Qi Tan, Huawen Huang   +4 more
doaj   +1 more source

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis. [PDF]

, 2016
A long-standing challenge in synthetic chemistry is the development of the transamidation reaction. This process, which involves the conversion of one amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors. Although some
Anthony, Sarah M, Baker, Emma L, Garg, Neil K, Yamano, Michael M, Zhou, Yujing   +4 more
core   +2 more sources