Results 31 to 40 of about 473,188 (208)
N-[2-(1H-Indol-3-yl)ethyl]-2-(4-isobutylphenyl)propanamide
The compound in the title was prepared by reaction between tryptamine and ibuprofen using N,N′-dicyclohexylcarbodiimide as a “dehydrating„ reagent.
Stanimir Manolov +2 more
doaj +1 more source
Breast cancer is a multifactor disease, and many drug combination therapies are applied for its treatment. Selenium derivatives represent a promising potential anti-breast cancer treatment.
Mikel Etxebeste-Mitxeltorena +8 more
doaj +1 more source
Ruthenium-Catalyzed Oxidative Amidation of Alkynes to Amides [PDF]
Complex CpRuCl(PPh3)2 catalyzes reactions of terminal alkynes with 4-picoline N-oxide and primary and secondary amines to afford the corresponding amides. The reactions occur in chlorinated solvent and aqueous medium, showing applications in peptide chemistry.
Andrea Álvarez-Pérez +4 more
openaire +5 more sources
pH Sensitive Anticancer Prodrug: Amide of Kemp's Acid [PDF]
Solid tumours are characterised by lower extracellular pH (as low as 5.8 pH) compared to normal healthy cellular pH (actively regulated at pH 7.3). This difference may be exploited with an acid-sensitive anti-tumour prodrug which releases a cytotoxin ...
Brooks, Robert Turongo
core
Amide-Directed, Rhodium-Catalyzed Enantioselective Hydrosilylation of Unactivated Internal Alkenes
Despite the recent advances made in the area of asymmetric hydrosilylation, metal-catalyzed enantioselective hydrosilylation of unactivated internal alkenes remains a challenge.
Huanrong Li (1476760) +3 more
core +1 more source
Carbon Dioxide Capture on Metal-organic Frameworks with Amide-decorated Pores [PDF]
CO2 is the main greenhouse gas emitted from the combustion of fossil fuels and is considered a threat in the context of global warming. Carbon capture and storage (CCS) schemes embody a group of technologies for the capture of CO2 from power plants ...
Sima Kazemi, Vahid Safarifard
doaj +1 more source
Medical radioactive isotopes play a very important role in disease diagnosis and treatment, with 99Tcm drugs being widely used in disease diagnosis. 99Tcm is primarily obtained from its parent nuclide, 99Mo, through a 99Mo/99Tcm generator. Currently, the
Tao-yuan XIU +7 more
doaj +1 more source
A series of myricetin derivatives containing amide, thioether, and 1,3,4-thiadiazole moieties were designed and synthesized, and their antiviral and antibacterial activities were assessed.
Xianghui Ruan +7 more
doaj +1 more source
Cyclic Peptoid-Peptide Hybrids as Versatile Molecular Transporters
Addressing intracellular targets is a challenging task that requires potent molecular transporters capable to deliver various cargos. Herein, we report the synthesis of hydrophobic macrocycles composed of both amino acids and peptoid monomers. The cyclic
Claudine Nicole Herlan +6 more
doaj +1 more source
Studies Towards a pH-Sensitive Anticancer Prodrug Model [PDF]
Tumour-activated prodrug (TAP) is designed to aim at increasing the prodrug selectivity to kill cancer cells. One strategy to is to design a TAP containing an amine cytotoxin, present as an amide function, which could be released more rapidly in the low ...
Teng, Xiao Shi
core

