Results 51 to 60 of about 460,138 (357)
MAS NMR detection of hydrogen bonds for protein secondary structure characterization [PDF]
, 2020 Hydrogen bonds are essential for protein structure and function, making experimental access to long-range interactions between amide protons and heteroatoms invaluable. Here we show that measuring distance restraints involving backbone hydrogen atoms and
Friedrich, Daniel +3 more
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Carbon Dioxide Capture on Metal-organic Frameworks with Amide-decorated Pores [PDF]
Nanochemistry Research, 2018 CO2 is the main greenhouse gas emitted from the combustion of fossil fuels and is considered a threat in the context of global warming. Carbon capture and storage (CCS) schemes embody a group of technologies for the capture of CO2 from power plants ...
Sima Kazemi, Vahid Safarifard
doaj +1 more source
Physical limit to concentration sensing amid spurious ligands [PDF]
Phys. Rev. Lett. 115, 038102 (2015), 2015 To adapt their behaviour in changing environments, cells sense concentrations by binding external ligands to their receptors. However, incorrect ligands may bind nonspecifically to receptors, and when their concentration is large, this binding activity may interfere with the sensing of the ligand of interest.
arxiv +1 more source
Two-dimensional Infrared Spectroscopy of vibrational polaritons of molecules in an optical cavity
, 2016 Strong coupling of molecular vibrations to an infrared cavity mode affects their nature by creating dressed polariton states. We show how the single and double vibrational polariton manifolds may be controlled by varying the cavity coupling strength, and
Mukamel, Shaul, Saurabh, Prasoon
core +1 more source
FEBS Open Bio, EarlyView.The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title molecule, C29H29N3O4S, adopts a conformation with the two phenyl substituents disposed on opposite sides of the mean plane of the isoquinoline unit.
Eman M. Sayed +7 more
doaj +1 more source
Weak Interactions in Dimethyl Sulfoxide (DMSO) -- Tertiary Amide Solutions: the Versatility of DMSO as a Solvent [PDF]
arXiv, 2022 The structures of equimolar mixtures of the commonly used polar aprotic solvents dimethylformamide (DMF) and dimethylacetamide (DMAc) in dimethylsulfoxide (DMSO) have been investigated via neutron diffraction augmented by extensive hydrogen/deuterium isotopic substitution.
arxiv
The effect of protein backbone hydration on the amide vibrations in Raman and Raman optical activity spectra [PDF]
, 2019 Raman and specifically Raman optical activity (ROA) spectroscopy are very sensitive to the solution structure and conformation of biomolecules. Because of this strong conformational sensitivity, density functional theory (DFT) calculations are often used
Bultinck, Patrick +2 more
core +2 more sources
Advanced Engineering Materials, EarlyView.This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing enhanced mechanical properties and biocompatibility, the hydrogels exhibit fast gelation, improved structural integrity, and reduced swelling. Their potential for
Raimundo Nonato Fernandes Moreira Filho +8 more
wiley +1 more source