Results 251 to 260 of about 72,922 (314)

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Unlocking the Silent Proteome: Chemoselective Asn/Gln Activation for Multidimensional Protein Diversification. [PDF]

J Am Chem Soc
Emenike B, Paikin ZE, Talbott JM, Lidskog A, Gia Le BQ, Swaminathan J, Anslyn EV, Raj M.   +7 more
europepmc   +1 more source

Accurate Measurements of Solvent Exchange in Asparagine and Glutamine Side-Chain NH₂ Groups of Proteins by <i>z</i>-Exchange NMR Spectroscopy. [PDF]

J Phys Chem Lett
Tugarinov V, Clore GM.
europepmc   +1 more source

Biochemical and Genetic Characterization of Ergot Alkaloid Biosynthesis in <i>Aspergillus aspearensis</i>. [PDF]

Toxins (Basel)
Fuss JL, Panaccione DG.
europepmc   +1 more source

Phosphine-Catalyzed Regio- and Stereoselective Umpolung Addition of Amides to Alkynoates: Access to Complex α,β-Dehydroamino Acid Derivatives. [PDF]

Org Lett
Buchbinder NW, Dunnavant KL, Bage AD, Beck ON, Harris KR, Gwinn RK, Santos WL.   +6 more
europepmc   +1 more source

Development of a Brain-Penetrant Nurr1 Agonist Tool. [PDF]

ChemMedChem
Vietor J, Stiller T, Gege C, Saeb W, López-García Ú, Kohlhof H, Vitt D, Merk D.   +7 more
europepmc   +1 more source

A Versatile Strategy for Head-to-Tail Macrocyclization and Traceless Backbone Editing of Short Peptides. [PDF]

J Am Chem Soc
Wall BJ, Chaudhury U, Sharma KK, Venditti V, VanVeller B.   +4 more
europepmc   +1 more source

Acyclic Twisted Amides

Chemical Reviews, 2021
In this contribution, we provide a comprehensive overview of acyclic twisted amides, covering the literature since 1993 (the year of the first recognized report on acyclic twisted amides) through June 2020.
Guangrong Meng, Jin Zhang, Michal Szostak   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Amide–Amide Hydrogen Bonding. Semirubin Amides

Monatshefte für Chemie - Chemical Monthly, 2006
Semirubins are analogs for one-half of the bilirubin structure and capable of intramolecular hydrogen bonding. Semirubin amides of ammonia and primary amines are also capable of intramolecular hydrogen bonding. From a combination of spectroscopic methods (1H NMR, NOE, and VPO), the primary amide is found to engage very effectively in intramolecular ...
Nicholas T. Salzameda, David A. Lightner
openaire   +1 more source

Peptide amidation

Trends in Biochemical Sciences, 1991
Many hormones, neurotransmitters and growth factors are peptides that carry an amide group at their carboxyl terminus which is essential for their biological activity. The amide is formed by hydroxylation of an additional glycine residue present in the biosynthetic precursor and the hydroxyglycine derivative dissociates to form the peptide amide and ...
A F, Bradbury, D G, Smyth
openaire   +2 more sources