Results 191 to 200 of about 79,537 (266)

PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer

open access: yesAdvanced Science, EarlyView.
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen   +7 more
wiley   +1 more source

Intrinsic charge polarization governs hydrogen-bonding strength in amide <i>vs.</i> imide self-association.

open access: yesPhys Chem Chem Phys
Lekanne Deprez S   +4 more
europepmc   +1 more source

Dehydrative Amidation of Carboxylic Acids via Organosilane Catalysis. [PDF]

open access: yesACS Omega
Gavit AV   +5 more
europepmc   +1 more source

Calcium‐Mechanochemistry Enabled Ketone Synthesis From Organic Iodides and Carboxylic Acids

open access: yesAdvanced Science, EarlyView.
Mechanochemically generated organocalcium species display unusual chemoselectivity toward carboxylates, enabling direct ketone synthesis without overaddition. Ball milling activates commercial calcium metal under ambient, solvent‐minimized conditions, providing a broad substrate scope, high functional‐group tolerance, and a practical one‐step ...
Mengyao Pei   +9 more
wiley   +1 more source

Cobalt photocatalysed carbonylation reactions in continuous flow.

open access: yesChem Commun (Camb)
Martínez-Aguirre M   +4 more
europepmc   +1 more source

Mechanochemical Piezoelectric Catalysis: Advancing the Hydrogenation of Alkenes

open access: yesAdvanced Science, EarlyView.
This study presents mechanochemical piezoelectric catalysis for alkene hydrogenation, eliminating the need for transition metals, H2, and solvents. The method effectively hydrogenates diverse activated and unactivated alkenes and shows potential for modifying bioactive molecules in pharmaceuticals.
Zixi Ai   +5 more
wiley   +1 more source

Gold(iii) complexes of 2-<i>tert</i>-butyl-1,10-phenanthroline and of <i>N</i>-(8-quinolinyl)amides: syntheses and structures. [PDF]

open access: yesRSC Adv
Weinberg DR   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy