Results 151 to 160 of about 21,421 (302)

Folate Interaction With Genetic Risk for Neural Tube Defects Among Infants in Bangladesh

Birth Defects Research, Volume 117, Issue 12, December 2025.
ABSTRACT Background Neural tube defects such as spina bifida (SB) are congenital anomalies associated with significant morbidity and mortality worldwide. Environmental factors, particularly folate, modify SB risk. Based on recurrence rates of SB within families, genetic risk also contributes to SB development.
Enrique Mondragon‐Estrada, Xingyan Wang, Michael D. Uhler, Afifah Farooque, Kelly Liu, Sudipta Kumer Mukherjee, Sheikh Muhammad Ekramullah, D. M. Arman, Joynul Islam, Hafiza Sultana Suchanda, David C. Christiani, Benjamin C. Warf, Maitreyi Mazumdar, Sarah U. Morton   +13 more
wiley   +1 more source

Opportunities and Challenges of the Application of Nuclear Magnetic Resonance‐Based Cerebrospinal Fluid Metabolomics for Clinical Research

Chemistry–Methods, Volume 5, Issue 12, November 2025.
Cerebrospinal fluid (CSF) is an important diagnostic matrix in neurology. This review illustrates the potentials and pitfalls of current CSF analysis by nuclear magnetic resonance. Created with BioRender.com in BioRender. Berezhnoy, G. (2025) https://BioRender.com/x80l903. Web of Science is owned by Clarivate.
Georgy Berezhnoy, Jannik Sprengel, Claire Cannet, Nils Pompe, Christoph Trautwein   +4 more
wiley   +1 more source

Genomic Architecture of Nestmate Recognition Cues in the Desert Ant

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study reveals for the first time the genomic basis for the chemical cues used by social insects for nestmate recognition. We conducted a GWAS to identify QTLs that explain quantitative variation in cuticular hydrocarbons among colonies from a population of the desert ant Cataglyphis niger. ABSTRACT Nestmate recognition is the basis for cooperation
Pnina Cohen, Shani Inbar, Eyal Privman
wiley   +1 more source

Detection of Inborn Errors of Metabolism using Tandem Mass Spectrometry among High-risk Omani Patients

Oman Medical Journal, 2012
Objectives: This is a report on the types and patterns of inborn errors of metabolism (IEMs) of amino acids, organic acids and fatty acids oxidation detected by Tandem Mass Spectrometry for a period of 10 years (1998-2008) at Sultan Qaboos University ...
Sulaiman Al Riyami, Matar Al Maney, Surendra Nath Joshi, Riad Bayoumi   +3 more
doaj  

Amino Acid Profile and Lactate Pyruvate Ratio: Potential Adjunct Markers for Differentiating Inborn Errors of Metabolism

Indian Journal of Clinical Biochemistry, 2019
Prajna P. Shetty, K. Nagendra, K. Nalini, P. Rao, N. Bhaskaranand, V. Belle   +5 more
semanticscholar   +1 more source

Regional Differences in Soybean Protein and Amino Acid Profiles: A Genetic Exploration Using a Novel GWAS Panel

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Regional differences in soybean seed protein and amino acid content in Canada present significant challenges for crop improvement and the market value of high‐protein livestock feed. This study employed genome‐wide association studies (GWAS) using a novel panel of 206 cultivars to investigate the genetic basis of regional variations.
Siwar Haidar, Simon Lackey, Aga Pajak, Mohamad S. Elian, Vi Nguyen, Jakob Bruggink, Loretta Ross, Fuyou Fu, Jonathan Durkin, Milad Eskandari, Ashkan Golshani, Zenglu Li, Lone Buchwaldt, Yuhai Cui, Anfu Hou, Yong‐Bi Fu, Krzysztof Szczyglowski, Elroy Cober, Frédéric Marsolais, Bahram Samanfar   +19 more
wiley   +1 more source

Comparative Effects of ZnO, MgO, and CaO Nanoparticles in 3D‐Printed Chitosan–Agarose Scaffolds on Antibacterial and Osteogenic Outcomes

Macromolecular Bioscience, Volume 25, Issue 12, December 2025.
3D‐bioprinted chitosan–agarose (CA) scaffolds loaded with calcium oxide (CAC), zinc oxide (CAZ), or magnesium oxide (CAM) nanoparticles (NPs) were developed. The NPs improved antibacterial activity, rheological properties, and bone marrow cell (BMC) proliferation.
Amir Hashemi, Masoumeh Ezati, Rima Paul, Inna Zumberg, Jaromir Bacovsky, Zdenka Fohlerova, Valentyna Provaznik   +6 more
wiley   +1 more source

PRMT1 in Health and Disease: Emerging Perspectives From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 6, Issue 12, December 2025.
Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo, Ying Gao, Xiaoliang Deng, Lei Wang, Tao Wu   +4 more
wiley   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

Six Years of Genetic Diagnosis of Severe Early‐Onset Obesity in a French Cohort

Obesity Science &Practice, Volume 11, Issue 6, December 2025.
ABSTRACT Objective Obesity is a multifactorial disease with a strong genetic component. It is imperative to enhance the identification of genetic variations in their early and severe manifestations in order to facilitate the development of personalized therapeutic strategies, informed clinical care, and the facilitation of genetic counseling.
M. Rama, E. Blond, A. Janin, M. Di‐Filippo, C. Cuerq, O. Marmontel, P. A. Rollat‐Farnier, E. Dieterlen, B. Segrestin, M. Nicolino, E. Disse, K. Perge, D. Collin‐Chavagnac   +12 more
wiley   +1 more source