Results 1 to 10 of about 4,195,373 (294)
Amino Acid Metabolism in Lupus [PDF]
Frontiers in Immunology, 2021 T cell metabolism is central to cell proliferation, survival, differentiation, and aberrations have been linked to the pathophysiology of systemic autoimmune diseases.
Michihito Kono +2 more
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Amino acid metabolism in health and disease
Signal Transduction and Targeted Therapy, 2023 Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth, differentiation and function.
Zhe-Nan Ling +5 more
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Dietary regulation on gut resistome linked with microbial amino acid metabolism in pigs [PDF]
Animal MicrobiomeDietary protein plays a crucial role in shaping the gut microbiome and modulating intestinal amino acid metabolism. Gut microbiome is recognized as a reservoir for carrying antimicrobial resistance genes.
Ziyu Liu +7 more
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Frontiers in Immunology, 2020 Cardiovascular disease is the leading global health concern and responsible for more deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory disease in the arterial wall, which underpins several types of cardiovascular
Bozidarka L. Zaric +8 more
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Amino Acid Metabolism in Health and Disease [PDF]
MedCommMetabolic reprogramming is a central feature of many human diseases, and therapies that target altered metabolic dependencies are moving from concept to clinical testing.
Zhiwei Su +7 more
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Decoding amino acid metabolism in hepatocellular carcinoma: critical nodes and novel therapeutic strategy [PDF]
Frontiers in OncologyAmino acid metabolic reprogramming is one of the crucial features of metabolic remodeling in HCC. Accumulating evidence indicates that specific amino acid metabolisms play essential roles in promoting HCC cell proliferation and the development of drug ...
Jiayi Zhang +19 more
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Amino acid metabolism modulates macrophage polarization: implications for autoimmune-related diseases [PDF]
Frontiers in ImmunologyAmino acid metabolic reprogramming is an important component of immunometabolism. In addition to providing biosynthetic substrates and energetic support for macrophages, distinct amino acid metabolic pathways can also reshape the inflammatory and ...
Yuzhe Yin +14 more
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Metabolism of Amino Acids in Cancer [PDF]
Frontiers in Cell and Developmental Biology, 2021 Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The uptake and metabolism of amino acids are aberrantly upregulated in many cancers that display addiction to particular amino acids. Amino acids facilitate the survival and proliferation of cancer cells under genotoxic, oxidative, and nutritional stress.
Zhen Wei +4 more
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Amino Acid Metabolism in Apicomplexan Parasites
Metabolites, 2021 Obligate intracellular pathogens have coevolved with their host, leading to clever strategies to access nutrients, to combat the host’s immune response, and to establish a safe niche for intracellular replication.
Aarti Krishnan, Dominique Soldati-Favre
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Amino acid metabolism in skeletal cells
Bone Reports, 2022 Amino acid metabolism regulates essential cellular functions, not only by fueling protein synthesis, but also by supporting the biogenesis of nucleotides, redox factors and lipids.
Claire-Sophie Devignes +2 more
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