Results 1 to 10 of about 270,080 (298)

L-Tryptophan Stimulates Bioactive Metabolite Accumulation and Cell Wall Remodelling in Flax Callus Cultures [PDF]

open access: yesMolecules
While L-tryptophan is a precursor of plant growth regulators, its effects on secondary metabolism, amino acid profile and cell wall organization in flax callus remain underexplored.
Kornelia L. Tudruj   +4 more
doaj   +2 more sources

In adult dogs is supplementary tryptophan in the diet effective in reducing signs of anxiety? [PDF]

open access: yesVeterinary Evidence
Question In adult dogs, is dietary supplementation with tryptophan compared with no dietary tryptophan supplement effective in reducing signs of anxiety?   Clinical bottom line The category of research question was: Treatment.
Lesca Sofyan
doaj   +2 more sources

Immunomodulatory, behavioral, and nutritional response of tryptophan application on poultry [PDF]

open access: yesVeterinary World, 2021
Tryptophan is an essential amino acid for all animals that was discovered through casein hydrolysis. The use of tryptophan as feed additives has been attracting the attention of many nutritionists because it cannot be synthesized enough in an animal's ...
Nguyen Thuy Linh   +2 more
doaj   +1 more source

Effect of Varying Levels of Dietary Tryptophan on Aggression and Abnormal Behavior in Growing Pigs

open access: yesFrontiers in Veterinary Science, 2022
Body lesions, resulting from tail-biting and ear-biting, can result in decreased health and welfare in pigs. Tryptophan, an indispensable amino acid, is needed to support protein deposition, and the synthesis of the neurotransmitter serotonin, which is ...
Maggie Henry   +4 more
doaj   +1 more source

Systemic tryptophan homeostasis

open access: yesFrontiers in Molecular Biosciences, 2022
Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin.
Simon Klaessens   +9 more
doaj   +1 more source

Tryptophan potentiates CD8+ T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Tryptophan catabolites suppress immunity. Therefore, blocking tryptophan catabolism with indoleamine 2,3-dioxygenase (IDO) inhibitors is pursued as an anticancer strategy.Methods The intracellular level of tryptophan and kynurenine was ...
Yan Huang   +10 more
doaj   +1 more source

Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications

open access: yes
Lasso peptides are a class of ribosomally synthesized and post-translationally modified peptides (RiPPs) defined by a macrolactam linkage between the N-terminus and the side chain of an internal aspartic acid or glutamic acid residue. Instead of adopting
Douglas A. Mitchell (1314975)   +5 more
core   +5 more sources

Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

open access: yesMetabolites, 2021
G-protein-coupled receptor-35 (GPR35) has been identified as a receptor for the tryptophan metabolite kynurenic acid (KynA) and suggested to modulate macrophage polarization in metabolic tissues.
Roland Baumgartner   +9 more
doaj   +1 more source

The Tryptophan and Kynurenine Pathway Involved in the Development of Immune-Related Diseases

open access: yes, 2023
The tryptophan and kynurenine pathway is well-known to play an important role in nervous, endocrine, and immune systems, as well as in the development of inflammatory diseases.
Asai Tomoko   +13 more
core   +1 more source

Glycated Tryptophan in the Plasma of Chickens Fed Tryptophan-excess Diets

open access: yesThe Journal of Poultry Science, 2015
When tryptophan is glycated with glucose, it results in forming two types of glycated tryptophan, glucose-tryptophan Amadori product and (1R, 3S)-1-(D- gluco-1,2,3,4,5-pentahydroxypentyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (PHP-THβC ...
Ryosuke Makino   +7 more
doaj   +1 more source

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