Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota-Associated Kynurenine Accumulation and Macrophage Remodeling. [PDF]
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Zhao S +9 more
europepmc +2 more sources
RETRACTED: Wigner et al. The Impact of Chronic Mild Stress and Agomelatine Treatment on the Expression Level and Methylation Status of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Brain Structures. <i>Genes</i> 2020, <i>11</i>, 1093. [PDF]
Wigner P +9 more
europepmc +1 more source
Epilepsy-Linked Gut Microbiota and Metabolic Signatures in Acquired Epilepsy: The Focus on Short-Chain Fatty Acid and Tryptophan Metabolism. [PDF]
Ravizza T +6 more
europepmc +1 more source
Antibiotic- and inducer-free biosynthesis of indican from crude glycerol using engineered probiotic Escherichia coli Nissle 1917. [PDF]
Mao LJ +8 more
europepmc +1 more source
Translating gut microbiome research into therapies for type 1 diabetes. [PDF]
Kok SP, Nieuwdorp M, Rampanelli E.
europepmc +1 more source
Tryptophan-Kynurenine Pathway Metabolites in Women Undergoing Caesarean Delivery. [PDF]
Ziętek M +7 more
europepmc +1 more source
<i>Lactobacillus reuteri</i> DSM 17938 and Its Supernatant Ameliorate Parkinson's Disease in Association with Modulation of Gut Microbiota and Its Tryptophan Metabolism. [PDF]
Su B +7 more
europepmc +1 more source
Amino acid- and lipid-related metabolic remodeling in PTZ-kindled mice reveals candidate plasma signatures of chronic epilepsy. [PDF]
Ren J, Wang F, Li Z, Liang Z, Liu S.
europepmc +1 more source
Altered tryptophan metabolism as a contributor to cognitive impairment in chronic kidney disease: a narrative review. [PDF]
Selvaraj H +5 more
europepmc +1 more source
The microgenderome in migraine: integrating sex hormones, microbial composition, and metabolic profiles into a sex-related framework. [PDF]
Fu J, Liu X, Liu D, Shen K, Yao M, Ni H.
europepmc +1 more source

