Results 31 to 40 of about 301,590 (287)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Extraction and Characterization of “Batuan” [Garcinia binucao (Blco.) Choisy] Seed Protein

open access: yesAnnals of Tropical Research, 2014
“Batuan” [Garcinia binucao (Blco.) Choisy], an indigenous, lesser known member of the Gutifferae family with export potential is underutilized and understudied.
Elizabeth S. Quevedo   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Egg Albumin Supplementation Decreases Isolation-Induced Aggression in Male White Mice

open access: yesAnnals of Tropical Research, 2015
There is a need to search for solutions of minimizing aggression so as to minimize violence. The purpose of the study is to determine the effects of different levels of egg albumin supplementation to the aggressive behavior of male white mice (Mus ...
Francis S. Legario   +1 more
doaj   +1 more source

The role of human and microbial metabolites of triptophane in severe diseases and critical ill (review) [PDF]

open access: yesКлиническая практика, 2020
The growing interest to metabolites circulating in the blood is associated with the accumulation of factual material on the involvement of low-molecular compounds in the development of a number of serious diseases.
M. L. Getsina   +2 more
doaj   +1 more source

ROTATIONAL SPECTRUM OF TRYPTOPHAN [PDF]

open access: yesProceedings of the 69th International Symposium on Molecular Spectroscopy, 2014
The rotational spectrum of the natural amino acid tryptophan has been observed for the first time using a combination of laser ablation, molecular beams, and Fourier transform microwave spectroscopy. Independent analysis of the rotational spectra of individual conformers has conducted to a definitive identification of two different conformers of ...
Sanz, Maria Eugenia   +3 more
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

UV-C-induced changes in a white wine: Evaluating the protective power of hydrolysable tannins and SO2

open access: yesOENO One
UV‑C treatment is a non-thermal technology that could be used for the microbiological stabilisation of must and wine. However, light - in this case UV‑C light - has an impact on wine.
Svetlana Cvetkova   +6 more
doaj   +1 more source

Effect of Chitosan and Amphiphilic Polymers on the Photosensitizing and Spectral Properties of Rose Bengal

open access: yesMolecules, 2022
The influence of chitosan (CS) and amphiphilic polymers (AP: pluronic F108 and polyvinylpyrrolidone (PVP)) on the photocatalytic activity of rose bengal (RB) in a model reaction of tryptophan photo-oxidation in phosphate-buffered saline (PBS) was studied.
Anastasia S. Kuryanova   +8 more
doaj   +1 more source

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