Results 1 to 10 of about 214,068 (119)
The Effects of Serotonin in Immune Cells
Frontiers in Cardiovascular Medicine, 2017 Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a peripheral hormone. Most of the body’s serotonin is circulating in the bloodstream, transported by blood platelets and is released upon activation.
Daniel Duerschmied +2 more
exaly +3 more sources
Serotonin syndrome: a clinical review of current controversies [PDF]
Journal of Integrative Neuroscience, 2020 Serotonin syndrome is a state of increased central and peripheral serotonin (5-hydroxytryptamine) activity. Unless recognized and treated early, serotonin syndrome can lead to seizures, shock and death.
Ursula Werneke +3 more
doaj +1 more source
Plasma Serotonin and Cardiovascular Outcomes in Chronic Kidney Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Platelet‐poor plasma serotonin levels are associated with adverse cardiovascular outcomes. Although plasma serotonin levels increase in chronic kidney disease, the cardiovascular implications remain unknown.
Daniel Edmonston +2 more
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Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment
Journal of Experimental & Clinical Cancer Research, 2021 Background Serotonin signaling has been associated with tumorigenesis and tumor progression. Targeting the serotonin transporter to block serotonin cellular uptake confers antineoplastic effects in various tumors, including colon cancer.
Di Ye +5 more
doaj +1 more source
Biomolecules, 2023 Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel +6 more
doaj +1 more source
Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission
Frontiers in Molecular Neuroscience, 2011 Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj +1 more source
Frontiers in Molecular Neuroscience, 2020 A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo +2 more
doaj +1 more source
Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts
Scientific Reports, 2021 Elevated blood serotonin levels have been observed in patients with heart failure and serotonin has a role in pathological cardiac function. The serotonin receptor system was examined in adult rat isolated cardiac fibroblast and myofibroblast cells. This
Emiri Tarbit +4 more
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Journal of Pharmacological Sciences, 2010 3,4-Methylenedioxymethamphetamine (MDMA) causes serotonin efflux via serotonin transporter. Recently, we have reported that sustained exposure to MDMA induced an augmentation of serotonin release in rat raphe serotonergic slice cultures.
Kazuki Nagayasu +4 more
doaj +1 more source
Cell Communication and Signaling, 2018 Background Besides its neurotransmitter and vasoconstriction functions, serotonin is an important mediator of numerous biological processes in peripheral tissues including cell proliferation, steatosis, and fibrogenesis.
Suryakant Niture +6 more
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