Role of serotonin on pituitary-thyroid functions and antioxidants in diabetic male rats
Diabetes mellitus causes an increase in oxidative stress. Serotonin is a hormone its level in circulation reduced in diabetes; recently, it has been found to possess antioxidant qualities.
Sumayah Faruq Kasim, Fouad Ziedan Hamzah
doaj +1 more source
Biological clocks in the duodenum and the diurnal regulation of duodenal and plasma serotonin. [PDF]
Serotonin in blood plasma is primarily synthesized in the duodenum, as brain derived serotonin does not cross the blood-brain barrier. Because serotonin in the brain and retina is synthesized under the control of a circadian clock, we sought to determine
Elizabeth Ebert-Zavos +3 more
doaj +1 more source
The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model [PDF]
One challenge of squamous cell carcinoma of the head and neck (SCCHN) chemotherapy is a small percentage of tumor cells that arrest in the G0 phase of the cell cycle and are thus not affected by chemotherapy. This could be one reason for tumor recurrence
Arnoldner, Christoph +6 more
core +1 more source
Serotonin receptor mechanisms in anti-depressant action [PDF]
Bibliography: leaves 221-270.Serotonin neurones have been implicated in the pathophysiology and treatment of clinical depression to a greater degree than any other neurotransmitter.
Quested, Digby John
core +1 more source
Serotonin and social norms : tryptophan depletion impairs social comparison and leads to resource depletion in a multiplayer harvesting game [PDF]
How do people sustain resources for the benefit of individuals and communities and avoid the tragedy of the commons, in which shared resources become exhausted?
Rogers, Robert D. +13 more
core +1 more source
Serotonin modulates Campylobacter jejuni physiology and in vitro interaction with the gut epithelium
Microbial endocrinology, which is the study of neurochemical-based host–microbe interaction, has demonstrated that neurochemicals affect bacterial pathogenicity.
Joshua M. Lyte +7 more
doaj +1 more source
Background: The off-target effects linezolid have the potential to cause serotonin syndrome when given in conjunction with serotonergic agents. Despite package insert labeling as a contraindication, several postmarketing studies have demonstrated a low ...
Xuping Yan +5 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The effects of glycogen synthase kinase-3beta in serotonin neurons. [PDF]
Glycogen synthase kinase-3 (GSK3) is a constitutively active protein kinase in brain. Increasing evidence has shown that GSK3 acts as a modulator in the serotonin neurotransmission system, including direct interaction with serotonin 1B (5-HT1B) receptors
Wenjun Zhou +9 more
doaj +1 more source

