Role of serotonin on pituitary-thyroid functions and antioxidants in diabetic male rats
Diabetes mellitus causes an increase in oxidative stress. Serotonin is a hormone its level in circulation reduced in diabetes; recently, it has been found to possess antioxidant qualities.
Sumayah Faruq Kasim, Fouad Ziedan Hamzah
doaj +1 more source
Serotonin modulates Campylobacter jejuni physiology and in vitro interaction with the gut epithelium
Microbial endocrinology, which is the study of neurochemical-based host–microbe interaction, has demonstrated that neurochemicals affect bacterial pathogenicity.
Joshua M. Lyte +7 more
doaj +1 more source
Serotonin receptor 5-HT1A initiates serotonin autoregulation in drosophila neurons
Access to thesis permanently restricted to Ball State community onlySerotonergic neurons produce extensively branched axons that fill most of the central nervous system, where they modulate behaviors such as mood, sleep, appetite, locomotion, and ...
Long, Delaney
core
Background: The off-target effects linezolid have the potential to cause serotonin syndrome when given in conjunction with serotonergic agents. Despite package insert labeling as a contraindication, several postmarketing studies have demonstrated a low ...
Xuping Yan +5 more
doaj +1 more source
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Noble, M. +2 more
core
The role of serotonin transmission in antidepressant drug actions
The simple aim of this thesis is to discuss the evidence that associates serotonin, serotonin receptors implicated in the pathophysiology of depression and the serotonin transporter (SERT) to the etiology of depression and the mechanisms that underly ...
Nwidadah, Charles
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The effects of glycogen synthase kinase-3beta in serotonin neurons. [PDF]
Glycogen synthase kinase-3 (GSK3) is a constitutively active protein kinase in brain. Increasing evidence has shown that GSK3 acts as a modulator in the serotonin neurotransmission system, including direct interaction with serotonin 1B (5-HT1B) receptors
Wenjun Zhou +9 more
doaj +1 more source
Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart
Serotonin (5-Hydroxytryptamine, 5-HT) can elicit both vasoconstrictive and relaxant responses on rat coronary artery. The constrictive response has been well discussed, but the mechanism of relaxant response is less studied.
Chien, Ching-Chia Chang;Hsin, Ling-Wei;Su, Ming-Jai +1 more
core +1 more source
5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release [PDF]
The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT3) receptors.
Moffat, Christopher +5 more
core +1 more source

