Results 11 to 20 of about 465,747 (346)
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
, 2005 Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Noble, M. +2 more
core +8 more sources
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment
Journal of Experimental & Clinical Cancer Research, 2021 Background Serotonin signaling has been associated with tumorigenesis and tumor progression. Targeting the serotonin transporter to block serotonin cellular uptake confers antineoplastic effects in various tumors, including colon cancer.
Di Ye +5 more
doaj +1 more source
The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy
Molecules, 2022 5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, D. Mirowska-Guzel
semanticscholar +1 more source
Role of serotonin receptor signaling in cancer cells and anti-tumor immunity
Theranostics, 2021 Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases.
Surojit Karmakar, G. Lal
semanticscholar +1 more source
Serotonin—Its Synthesis and Roles in the Healthy and the Critically Ill
International Journal of Molecular Sciences, 2021 Serotonin (5-hydroxytryptamine, 5-HT) plays two important roles in humans—one central and the other peripheral—depending on the location of the 5-HT pools of on either side of the blood-brain barrier.
M. Káňová, P. Kohout
semanticscholar +1 more source
Serotonin Syndrome/Serotonin Toxicity [PDF]
Federal Practitioner, 2020 This review of serotonin syndrome or serotonin toxicity covers the years 2014 to 2019, including information on pathophysiology, etiology, and diagnosis, 3 criteria for diagnosing serotonin syndrome, and criteria for neuroleptic malignant syndrome.The review highlights the potential lethal combinations of commonly prescribed medications used to treat ...
openaire +2 more sources
Serotonin regulation of behavior via large-scale neuromodulation of serotonin receptor networks
Nature Neuroscience, 2022 Although we understand how serotonin receptors function at the single-cell level, what role different serotonin receptors play in regulating brain-wide activity and, in turn, human behavior, remains unknown. Here, we developed transcriptomic–neuroimaging
P. Salvan +5 more
semanticscholar +1 more source
Biomolecules, 2023 Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel +6 more
doaj +1 more source
Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission
Frontiers in Molecular Neuroscience, 2011 Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj +1 more source
Frontiers in Molecular Neuroscience, 2020 A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo +2 more
doaj +1 more source