Results 11 to 20 of about 307,503 (301)

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Noble, M., Drake-Holland, A.J., Belcher, P.R.   +2 more
core   +9 more sources

Serotonin, how to find it... [PDF]

, 2013
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system (CNS) of animals, including humans ...
Crespi, Francesco
core   +1 more source

Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts

Scientific Reports, 2021
Elevated blood serotonin levels have been observed in patients with heart failure and serotonin has a role in pathological cardiac function. The serotonin receptor system was examined in adult rat isolated cardiac fibroblast and myofibroblast cells. This
Emiri Tarbit, Indu Singh, Jason Nigel Peart, Svetlana Bivol, Roselyn Barbara Rose’Meyer   +4 more
doaj   +1 more source

Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway

Cell Communication and Signaling, 2018
Background Besides its neurotransmitter and vasoconstriction functions, serotonin is an important mediator of numerous biological processes in peripheral tissues including cell proliferation, steatosis, and fibrogenesis.
Suryakant Niture, Maxwell A. Gyamfi, Habib Kedir, Elena Arthur, Habtom Ressom, Gagan Deep, Deepak Kumar   +6 more
doaj   +1 more source

Serotonin syndrome triggered by postoperative administration of serotonin noradrenaline reuptake inhibitor (SNRI)

JA Clinical Reports, 2019
Background Serotonin syndrome is a rare but potentially severe disease, which is caused by hyperstimulation of serotonin receptors in the central nervous system.
Junko Takata, Tomoko Arashi, Ayako Abe, Shoko Arai, Naoko Haruyama   +4 more
doaj   +1 more source

Telotristat ethyl reverses myxomatous changes in mice mitral valves

Frontiers in Cardiovascular Medicine, 2022
RationaleMyxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse.
Xinmei Wang, Danielle Kuban-Johnston, Pablo Lapuerta, Carla M. R. Lacerda   +3 more
doaj   +1 more source

Serotonin and Hallucinogens [PDF]

Neuropsychopharmacology, 1999
This brief review traces the serotonin (5-HT) hypothesis of the action of hallucinogenic drugs from the early 1950s to the present day. There is now converging evidence from biochemical, electrophysiological, and behavioral studies that the two major classes of psychedelic hallucinogens, the indoleamines (e.g., LSD) and the phenethylamines (e.g ...
G K, Aghajanian, G J, Marek
openaire   +2 more sources

Herpes Simplex Virus-1 Induced Serotonin-Associated Metabolic Pathways Correlate With Severity of Virus- and Inflammation-Associated Ocular Disease

Frontiers in Microbiology, 2022
Herpes simplex virus-associated diseases are a complex interaction between cytolytic viral replication and inflammation. Within the normally avascular and immunoprivileged cornea, HSV ocular infection can result in vision-threatening immune-mediated ...
Diana Marie Battaglia, Maria D. Sanchez-Pino, Maria D. Sanchez-Pino, Maria D. Sanchez-Pino, Charles D. Nichols, Timothy P. Foster, Timothy P. Foster, Timothy P. Foster, Timothy P. Foster   +8 more
doaj   +1 more source

Conformationally Flexible Dimeric-Serotonin-Based Sensitive and Selective Electrochemical Biosensing Strategy for Serotonin Recognition

, 2022
A novel electrochemical sensor was constructed based on an enzyme-mediated physiological reaction between neurotransmitter serotonin per-oxidation to reconstruct dual-molecule 4,4′-dimeric-serotonin self-assembled derivative, and the potential biomedical
Min-Ho Lee (1567513), Sachin Ganpat Chavan (6576569), Ajay Kumar Yagati (1561576), Sangho Yeon (14161108), Taek Lee (1561579), Anna Go (14161105), Aneesh Koyappayil (14161102)   +6 more
core   +1 more source

Localization of the Serotonin Transporter in the Dog Intestine and Comparison to the Rat and Human Intestines

Frontiers in Veterinary Science, 2022
Serotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. The serotonin transporter (SERT), responsible for serotonin reuptake and signaling termination, plays a prominent role in ...
Roberto Chiocchetti, Giorgia Galiazzo, Fiorella Giancola, Claudio Tagliavia, Chiara Bernardini, Monica Forni, Marco Pietra   +6 more
doaj   +1 more source