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Serotonin syndrome—A focused review
Basic and Clinical Pharmacology and Toxicology, 2023 Background: Serotonin syndrome is a potentially life-threatening syndrome with manifestations spanning from mild adverse effects to life-threatening toxicity. The syndrome is caused by overstimulation of serotonin receptors by serotonergic drugs.
Sidsel Arnspang Pedersen +2 more
exaly +5 more sources
Linezolid and serotonin syndrome [PDF]
Journal of International Medical ResearchLinezolid, a synthetic oxazolidinone antibiotic, is used to treat gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus .
Haytham A. Wali
doaj +4 more sources
Therapeutic Advances in Psychopharmacology, 2019 Serotonin syndrome is thought to arise from serotonin excess. In many cases, symptoms are mild and self-limiting. But serotonin syndrome can become life threatening, when neuromuscular hyperexcitability spins out of control.
Michael Ott +3 more
doaj +3 more sources
Serotonin syndrome: a clinical review of current controversies [PDF]
Journal of Integrative Neuroscience, 2020 Serotonin syndrome is a state of increased central and peripheral serotonin (5-hydroxytryptamine) activity. Unless recognized and treated early, serotonin syndrome can lead to seizures, shock and death.
Ursula Werneke +3 more
doaj +2 more sources
Serotonin Syndrome/Serotonin Toxicity [PDF]
Federal Practitioner, 2020 This review of serotonin syndrome or serotonin toxicity covers the years 2014 to 2019, including information on pathophysiology, etiology, and diagnosis, 3 criteria for diagnosing serotonin syndrome, and criteria for neuroleptic malignant syndrome.The review highlights the potential lethal combinations of commonly prescribed medications used to treat ...
Cynthia Wright Talton
openaire +3 more sources
High risk and low prevalence diseases: Serotonin syndrome
American Journal of Emergency Medicine, 2022 INTRODUCTION Serotonin syndrome is a rare, frequently misdiagnosed, serious condition with high morbidity. OBJECTIVE This review highlights the pearls and pitfalls of serotonin syndrome, including diagnosis, initial resuscitation, and management in the
Brit Long, Alex Koyfman
exaly +2 more sources
Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database [PDF]
Frontiers in PharmacologyBackgroundThis study aims to identify drugs associated with serotonin syndrome in elderly patients by utilizing the FDA Adverse Event Reporting System (FAERS), to provide evidence-based references for safe clinical medication practices.MethodsThis study ...
Xiaozhi Li +11 more
doaj +2 more sources
Serotonin Syndrome: Pathophysiology, Clinical Features, Management, and Potential Future Directions
International Journal of Tryptophan Research, 2019 Serotonin syndrome (SS) (also referred to as serotonin toxicity) is a potentially life-threatening drug-induced toxidrome associated with increased serotonergic activity in both the peripheral (PNS) and central nervous systems (CNS).
Lisa Hill +2 more
exaly +2 more sources
Management of serotonin syndrome (toxicity). [PDF]
Br J Clin PharmacolSerotonin syndrome (toxicity), resulting from an excessive accumulation of serotonin in the central nervous system, it can occur due to various factors such as the initiation of medication, overdose or drug interactions.
Chiew AL, Isbister GK.
europepmc +2 more sources
The Serotonin Syndrome: From Molecular Mechanisms to Clinical Practice
International Journal of Molecular Sciences, 2019 The serotonin syndrome is a medication-induced condition resulting from serotonergic hyperactivity, usually involving antidepressant medications. As the number of patients experiencing medically-treated major depressive disorder increases, so does the ...
Anthony Bonavía +2 more
exaly +2 more sources