The Association of Serotonin Toxicity with Combination Linezolid–Serotonergic Agent Therapy: A Systematic Review and Meta-Analysis [PDF]
Linezolid (LZD) has a longstanding reported association with the onset of serotonin toxicity (ST), secondary to drug–drug interactions with serotoninergic agents. There have been no conclusive data supporting the incidence or contributing risk factors to
Savanna SanFilippo +4 more
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Drug interaction between a selective serotonin reuptake inhibitor and a triptan leading to serotonin toxicity: a case report and review of the literature [PDF]
Background Serotonin toxicity is a known side effect of selective serotonin reuptake inhibitors and has previously also been described as a possible side effect of 5-hydroxytryptamine receptor agonist (triptan) medications.
Gilbert Jin, Philip Stokes
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Serotonin toxicity is a common but often unrecognized toxicological condition. In most cases, a combination of two or more serotonergic drugs can cause serotonin syndrome.
Gholamali Dorooshi +2 more
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Protracted escitalopram discontinuation syndrome and serotonin toxicity associated with CYP2C19 poor metabolism: A case report [PDF]
Serotonin-related adverse drug reactions (ADRs) of selective serotonin reuptake inhibitors, including serotonin toxicity (ST) and antidepressant discontinuation syndrome (ADS), may significantly affect adherence to antidepressant therapy.
Elizabeth H. Tran, PharmD +4 more
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Serotonin Syndrome versus Cannabis Toxicity in the Emergency Department [PDF]
As more states legalize marijuana, the potential of marijuana abuse could lead to an increase in the number of emergency department (ED) visits. We describe two patients who presented to the ED with dilated pupils, rigidity in both lower extremities, and
Jacob W. Baltz, Lamanh T. Le
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Serotonin and noradrenaline reuptake inhibitors improve micturition control in mice. [PDF]
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Marco Redaelli +6 more
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Transient Serotonin Toxicity Evoked by Combination of Electroconvulsive Therapy and Fluoxetine [PDF]
The serotonin syndrome has been described only in rare instances for electroconvulsive therapy combined with an antidepressant medication. We describe a case of serotonin toxicity induced by electroconvulsive therapy in combination with fluoxetine.
René Klysner +2 more
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Functional Pharmacobezoar and Bowel Ischemia Requiring Hemicolectomy Complicating Extended-Release Carbamazepine-Venlafaxine Overdose [PDF]
BACKGROUND:. Overdoses of extended-release (ER) medications can cause life-threatening toxicity from prolonged gastrointestinal drug retention due to pharmacobezoar formation.
Mirna Gerges, MScOT +2 more
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Tetrodotoxin Oral Film Attenuates Depression in a Chronic Unpredictable Mild Stress Model in Mice [PDF]
Depression remains a major global health challenge, with a significant proportion of patients failing to respond to conventional antidepressants. This study aimed to evaluate the potential antidepressant effects and toxicological profile of a novel ...
Jianlin He +5 more
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Opioids induced serotonin toxicity? Think again
Vandana Sharma +2 more
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