The Association of Serotonin Toxicity with Combination Linezolid–Serotonergic Agent Therapy: A Systematic Review and Meta-Analysis [PDF]
Pharmacy, 2023 Linezolid (LZD) has a longstanding reported association with the onset of serotonin toxicity (ST), secondary to drug–drug interactions with serotoninergic agents. There have been no conclusive data supporting the incidence or contributing risk factors to
Savanna SanFilippo +4 more
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Drug interaction between a selective serotonin reuptake inhibitor and a triptan leading to serotonin toxicity: a case report and review of the literature [PDF]
Journal of Medical Case Reports, 2021 Background Serotonin toxicity is a known side effect of selective serotonin reuptake inhibitors and has previously also been described as a possible side effect of 5-hydroxytryptamine receptor agonist (triptan) medications.
Gilbert Jin, Philip Stokes
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Serotonin toxicity following suicide with citalopram and lamotrigine: A rare case report and literature review [PDF]
Journal of Research in Pharmacy Practice, 2020 Serotonin toxicity is a common but often unrecognized toxicological condition. In most cases, a combination of two or more serotonergic drugs can cause serotonin syndrome.
Gholamali Dorooshi +2 more
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Protracted escitalopram discontinuation syndrome and serotonin toxicity associated with CYP2C19 poor metabolism: A case report [PDF]
Mental Health ClinicianSerotonin-related adverse drug reactions (ADRs) of selective serotonin reuptake inhibitors, including serotonin toxicity (ST) and antidepressant discontinuation syndrome (ADS), may significantly affect adherence to antidepressant therapy.
Elizabeth H. Tran, PharmD +4 more
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Opioids induced serotonin toxicity? Think again
Indian Journal of Anaesthesia, 2015 Sir, In a recently published article, ‘Cardiac arrest from tramadol and fentanyl combination’ by Nair and Chandy,[1] the authors concluded this case to be the first ever report of serotonin toxicity due to the co-administration of fentanyl and tramadol.
Vandana Sharma +2 more
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Case Report: Complex venlafaxine overdose and prolonged intensive care unit hospitalization associated to combined CYP2D6 and CYP2C19 polymorphisms [PDF]
Frontiers in PsychiatryIntroductionVenlafaxine (VEN) undergoes extensive hepatic metabolism, mainly via CYP2D6. Other minor pathways are also involved in VEN metabolism, some of which have clinical significance, such as the CYP2C19 pathway.
Bruno Michel +5 more
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European Psychiatry, 2021 Introduction Serotonin syndrome (SS) is a toxic state characterized by increased serotonin activity. It has been suggested that severe serotonin syndrome usually involves monoaminoxidase inhibitors (MAOIs). Objectives To quantify in how far severe SS
P. Truedson +5 more
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Serotonin syndrome: a rare undiagnosed cause of hyperpyrexia
The Egyptian Journal of Internal Medicine, 2023 Serotonin syndrome (SS) is a rare but potentially life-threatening condition, and it is caused by increasing serotonergic activities. It is an underdiagnosed and under-reported condition.
Hamdy Ibrahim +8 more
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Comparative Study of the Acute Toxicity of Fluoxetine Versus Amitriptyline and the Predictive Factors for Their Complications [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2016 The aim of this study is to compare acute toxicity of fluoxetine versus that of amitriptyline among patients admitted to the Poison Control Centre, Ain Shams University (PCC-ASU) and to investigate some predictive factors for the development of ...
Eglal ELawady, Gihan Azab
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Index finger pointing posture in a patient with drug-induced foot tremor
Clinical Parkinsonism & Related Disorders, 2021 A 41-year-old woman who had been taking paroxetine began taking tramadol for bilateral ankle pain. A few days later, the patient presented acutely with both feet tremors.
Gohei Yamada +3 more
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