Results 1 to 10 of about 4,795 (207)

Ultrasensitive Immunochromatographic Strip for Detection of Cyproheptadine

open access: yesFood and Agricultural Immunology, 2018
Using immunological and cell fusion technology, group-specific monoclonal antibodies were produced against cyproheptadine. The 50% inhibitory concentration of the antibody for cyproheptadine was 0.37 ng/mL, the linear range was 0.16–0.85 ng/mL, and ...
Liqiang Liu, Hua Kuang, Gang Cui
exaly   +3 more sources

Repurposing the antihistamine cyproheptadine for osteoarthritis: nothing to sneeze at [PDF]

open access: yesThe Journal of Clinical Investigation
Osteoarthritis (OA) is a highly prevalent and painful joint disease in desperate need of disease-modifying therapeutics. Decline in the activity of the Forkhead box O (FOXO) family of transcriptional regulators in articular chondrocytes may contribute to
Richard F. Loeser, Philip R. Coryell
doaj   +3 more sources

Cyproheptadine-Induced Obsessive-Compulsive Symptoms in a Preschool Child

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local-anesthetic properties. It has been shown effective as an appetite stimulant in the treatment of young children with feeding difficulties and ...
Ilyas Kaya, Funda Suleyman, Murat Coskun
doaj   +2 more sources

Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review [PDF]

open access: yesFrontiers in Pediatrics, 2021
Objectives: Cyproheptadine is a first-generation H1-antihistamine drug first that was distributed in the 1960s. While its orexigenic effect was observed early, cyproheptadine is not yet authorized for this indication in all countries today.
Valérie Bertrand   +10 more
doaj   +2 more sources

The Effectiveness of Cyproheptadine as a Treatment Option for Cats with Eosinophilic Airway Inflammation [PDF]

open access: yesVeterinary Evidence
Question In cats with eosinophilic airway inflammation does cyproheptadine compared with no treatment result in a reduction in severity of clinical signs?   Clinical bottom line The category of research question was: Treatment. The number and
Jillian Seeman   +2 more
doaj   +2 more sources

Histamine H1 receptor inverse agonists improve structure and pain in an osteoarthritis mouse model [PDF]

open access: yesThe Journal of Clinical Investigation
Osteoarthritis (OA) is the most common joint disease. Controlling the complex pathogenesis is challenging, thus, disease-modifying OA drugs are not available.
Ichiro Kurakazu   +7 more
doaj   +2 more sources

Lifestyle and SSRI Interventions in Pediatric Cyclic Vomiting Syndrome: Rethinking First-Line Management [PDF]

open access: yesChildren
Background: Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder characterized by recurrent episodes of intense nausea and vomiting.
Cansu Altuntaş   +3 more
doaj   +2 more sources

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates [PDF]

open access: yesFrontiers in Pharmacology
Background: Parkinson's disease (PD), a prevalent and progressive neurodegenerative disorder, currently lacks effective and satisfactory pharmacological treatments.
Xin Guo   +9 more
doaj   +2 more sources

Fexofenadine HCl enhances growth, biofilm, and lactic acid production of Limosilactobacillus reuteri and Bifidobacterium longum: implications for allergy treatment [PDF]

open access: yesBMC Microbiology
Background It is evident that various drugs influence the gut microbiota, yet the precise mechanism driving these effects remain ambiguous. Considering the growing recognition of gut microbiota’s role in health and disease, it is important to explore how
Zainab Kamel Hammouda   +2 more
doaj   +2 more sources

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

open access: yesFrontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci   +11 more
doaj   +1 more source

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