Results 31 to 40 of about 228 (135)

Anticholinergic Medication Burden Scales: A Systematic Review

Journal of the American Geriatrics Society, Volume 74, Issue 6, Page 1771-1784, June 2026.
ABSTRACT Background Anticholinergic burden refers to the cumulative anticholinergic effect of all medications taken by an individual. Anticholinergic burden scales help identify patients at risk of anticholinergic adverse effects and guide prescribing. However, substantial variation exists between scales, with no gold standard identified.
Orla Vennard, Carrie Stewart, Mansi Tolia, Roy L. Soiza, Phyo K. Myint   +4 more
wiley   +1 more source

Cyproheptadine Treatment in Children and Adolescents with Migraine: A Retrospective Study in Japan

Neurology International
Objective: Evidence on prophylactic drugs for pediatric migraine is limited, especially when comorbid conditions contribute to treatment resistance. This study evaluated the efficacy of cyproheptadine in children with migraine and explored the impact of ...
Hideki Shimomura, Sachi Tokunaga, Eisuke Terasaki, Naoko Taniguchi, Yohei Taniguchi, Saeka Yoshitake, Yuki Terakita, Kenji Inoue, Masumi Okuda, Takeo Kato, Yasuhiro Takeshima   +10 more
doaj   +1 more source

Reversible cerebral vasoconstriction syndrome: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1162-1180, May 2026.
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa, Abner da Silva Machado, Arthur de Oliveira Veras, Thiago Oscar Goulart, Sarah Galassi Tatsuta, Trajano Aguiar Pires Gonçalves, Eva Rocha, Octávio Marques Pontes‐Neto   +7 more
wiley   +1 more source

The role of peripheral serotonin in SARS‐CoV‐2 infectivity, COVID‐19 treatment and long COVID

Immunology &Cell Biology, Volume 104, Issue 4, Page 368-376, April 2026.
In this article, we discuss how SARS‐CoV‐2 infects the gastrointestinal tract, that enterochromaffin cells, the source of circulating serotonin, uniquely express viral entry receptors. We examine how this infection disrupts gut‐derived serotonin, contributing to gastrointestinal symptoms and disease severity, and link elevated plasma serotonin to COVID‐
Daniel W Thorpe, Lauren A Jones, Alyce M Martin, Rosemary A Coleman, Caitlin Allman, Rochelle A Peterson, Damien J Keating   +6 more
wiley   +1 more source

Isometric handgrip contraction increases tibialis anterior intrinsic motoneuron excitability in a dose‐dependent manner

Experimental Physiology, Volume 111, Issue 4, Page 2200-2213, 1 April 2026.
Abstract The contribution of persistent inward currents (PICs) to motoneuron firing in the lower limb typically increases after a remote handgrip contraction, believed to result from diffuse serotonergic input increases in spinal cord. We investigated whether handgrip contraction intensity, duration and/or impulse would affect PIC estimates in tibialis
Lucas Ugliara, Lucas B. R. Orssatto, Amilton Vieira, Gabriel S. Trajano   +3 more
wiley   +1 more source

Comparative evaluation of cyproheptadine and mirtazapine in enhancing post-surgical appetite in rabbits following ovariohysterectomy

Letters in Animal Biology
Ovariohysterectomy (OHE) is a fundamental surgical procedure for companion animal population control and the prevention of life-threatening reproductive diseases, significantly improving animal welfare.
Parham Rahmanian, MohammadArad Zandieh, Alireza Jahandideh, Ahmad Asghari   +3 more
doaj   +1 more source

Role of cyproheptadine in chronic urticaria not controlled with second-generation antihistamines: a retrospective study [PDF]

Exploration of Immunology
Aim: This retrospective study was performed to evaluate the efficacy and tolerability of cyproheptadine versus montelukast as adjuncts to ongoing second-generation antihistamines in adults with refractory chronic urticaria.
Shambo S. Samajdar, Anupam Das, Saibal Moitra, Shatavisa Mukherjee, Nandini Chatterjee, Shashank R. Joshi   +5 more
doaj   +1 more source

Managing Antidepressant‐Induced Hyperhidrosis With Vitamin E: An Over‐the‐Counter Supplement–Based Approach

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Excessive sweating is a common side effect of antidepressants, affecting approximately 22% of patients. Antidepressant‐induced excessive sweating (ADIES) can significantly impair quality of life and medication adherence. This case report explores the use of Vitamin E as a novel adjunct treatment for ADIES.
Saad Nazir, Mahnoor Azmat, Neha Prathivadi, Divyaraj Bavishi, Yasin Ibrahim   +4 more
wiley   +1 more source

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

Frontiers in Pharmacology
Background: Parkinson's disease (PD), a prevalent and progressive neurodegenerative disorder, currently lacks effective and satisfactory pharmacological treatments.
Xin Guo, Xin Guo, Jie Wang, Hongyang Fan, Wanying Tao, Zijing Ren, Xingyue Li, Suyu Liu, Peiyang Zhou, Yingzhu Chen   +9 more
doaj   +1 more source

EFFECT OF CYPROHEPTADINE* ON GROWTH, FOOD UTILIZATION EFFICIENCY AND CARCASS COMPOSITION IN SHEEP [PDF]

Assiut Veterinary Medical Journal, 1977
Eighteen Osimi rams were used in this experiment to study the effect of Cyproheptadine, when mixed with the ration, on body weight, food efficiency and carcass quality.
H.M. Abdel-Hafeez, S.M. Tony
doaj   +1 more source