Results 41 to 50 of about 72,544 (286)
The serotonin syndrome as a result of mephedrone toxicity [PDF]
BMJ Case Reports, 2010 A 22-year-old male presented to an emergency department by ambulance. His clinical picture included tachycardia, diaphoresis, hypertonia, hyper-reflexia and clonus. The patient became hyperthermic and deteriorated over the next hour. The principal substance ingested was mephedrone and appropriate treatment for the serotonin syndrome resulted in a ...
Gerard, Garrett, Michael, Sweeney
openaire +2 more sources
Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important [PDF]
, 2015 Kynurenine pathway, the quantitatively main branch of tryptophan metabolism, has been long been considered a source of nicotinamide adenine dinucleotide, although several of its products, the so-called kynurenines, are endowed with the capacity to ...
CURTO, MARTINA +4 more
core +1 more source
Uptake, accumulation and metabolization of the antidepressant fluoxetine by Mytilus galloprovincialis [PDF]
, 2016 Fluoxetine, a selective serotonin re-uptake inhibitor (SSRI) antidepressant, is among the most prescribed pharmaceutical active substances worldwide. This study aimed to assess its accumulation and metabolization in the mussel Mytillus galloprovincialis,
André M.P.T. Pereira +39 more
core +1 more source
Cyproheptadine in serotonin syndrome: A retrospective study
Journal of Family Medicine and Primary CareObjective: Serotonin syndrome (SS) is an iatrogenic life-threatening condition caused by serotonergic agents. The treatment for SS involves the administration of a serotonin antagonist (cyproheptadine).
Sanjay Prakash +3 more
doaj +1 more source
Methylene Blue Causing Serotonin Syndrome Following Cystocele Repair
Urology Case Reports, 2016 Methylene blue is an intravenously administered agent that may potentiate serotonin syndrome. The usage of methylene blue to evaluate ureters for injuries and patency during urological surgeries is recognized as common practice.
Kailash Kapadia +5 more
doaj +1 more source
Frontiers in Pharmacology, 2019 Halogenated derivatives of amphetamine-type stimulants are appearing on the drug market, often with altered pharmacological profile and sometimes different legal status compared to the non-halogenated substances.
Dino Luethi +6 more
doaj +1 more source
Case Reports in Psychiatry, 2023 Serotonin syndrome, also known as serotonin toxicity, is associated with increased serotonergic activity in the central and the peripheral nervous system. The symptoms can range from mild to potentially life threatening.
Rohit Madan +3 more
doaj +1 more source
Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure
Ecotoxicology and Environmental Safety, 2021 Sertraline (SER) is one of the most frequently detected antidepressant drugs in aquatic environments. However, knowledge regarding SER-induced behavioral alterations in fish is insufficient, as well as the mechanisms underlying SER-induced toxicity.
Huiting Yang +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Applied Sciences, 2021 The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits their concentration.
Bárbara Costa +4 more
doaj +1 more source