Results 21 to 30 of about 72,544 (286)

Procarbazine and antidepressants: a retrospective review of the risk of serotonin toxicity [PDF]

open access: yes, 2013
Background Procarbazine is an anticancer agent that also inhibits monoamine oxidase, an enzyme responsible for the metabolism of various catecholamines, including serotonin.
Baker, Nicole M.   +3 more
core   +1 more source

Predicting serotonin toxicity in serotonin reuptake inhibitor overdose

open access: yesClinical Toxicology, 2022
We aimed to investigate the frequency of serotonin toxicity following overdose of antidepressants that inhibit serotonin reuptake and the factors that influence the probability of serotonin toxicity occurring. This was a retrospective cohort study of overdoses that included selective serotonin reuptake inhibitors (SSRIs) (70%) and serotonin ...
Joyce Cooper   +2 more
openaire   +3 more sources

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

open access: yes, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO   +6 more
core   +1 more source

Recreational use, analysis and toxicity of tryptamines [PDF]

open access: yes, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio   +3 more
core   +1 more source

Using a new high-throughput video-tracking platform to assess behavioural changes in Daphnia magna exposed to neuro-active drugs [PDF]

open access: yes, 2019
© 2019. ElsevierOne of the major challenges that faces today regulatory risk assessment is to speed up the way of assessing threshold sublethal detrimental effects of existing and new chemical products.
Barata Martí, Carlos   +8 more
core   +1 more source

Knowledge, attitude, and practice (KAP) Study on Serotonin Syndrome Among Neuro Physicians

open access: yesAnnals of Indian Academy of Neurology, 2020
Background and Aims: Serotonin syndrome (SS) is a highly underdiagnosed drug-induced clinical syndrome. Under diagnosis is partly due to the unawareness of this syndrome by physicians.
Sanjay Prakash   +2 more
doaj   +1 more source

Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]

open access: yes, 2017
This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V.   +4 more
core   +2 more sources

Serotonergic agents and linezolid: Impact of exposure to more than one agent concomitantly on risk of adverse effects

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: The off-target effects linezolid have the potential to cause serotonin syndrome when given in conjunction with serotonergic agents. Despite package insert labeling as a contraindication, several postmarketing studies have demonstrated a low ...
Xuping Yan   +5 more
doaj   +1 more source

Effects of MDMA on body temperature in humans [PDF]

open access: yes, 2014
Hyperthermia is a severe complication associated with the recreational use of 3,4-methylenedioxymethamphetamine(MDMA, Ecstasy). In this review, the clinical laboratory studies that tested the effects of MDMA on body temperature are summarized.
Liechti, Matthias E.
core   +1 more source

The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity [PDF]

open access: yesQJM, 2003
There are difficulties with the diagnosis of serotonin toxicity, particularly with the use of Sternbach's criteria.To improve the criteria for diagnosing clinically significant serotonin toxicity.Retrospective analysis of prospectively collected dataWe studied all patients admitted to the Hunter Area Toxicology Service (HATS) following an overdose of a
Dunkley, E. J. C.   +4 more
openaire   +2 more sources

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