Results 21 to 30 of about 418,334 (279)

L-Tryptophan Stimulates Bioactive Metabolite Accumulation and Cell Wall Remodelling in Flax Callus Cultures

Molecules
While L-tryptophan is a precursor of plant growth regulators, its effects on secondary metabolism, amino acid profile and cell wall organization in flax callus remain underexplored.
Kornelia L. Tudruj, Michał Piegza, Lucyna Dymińska, Maja Słupczyńska, Magdalena Wróbel-Kwiatkowska   +4 more
doaj   +1 more source

Effects of Dietary Supplementation of Acetate and L-Tryptophan Conjugated Bypass Amino Acid on Productivity of Pre- and Post-Partum Dairy Cows and Their Offspring

Animals, 2021
In this study, we investigated the effect of dietary supplementation with acetate and L-tryptophan-conjugated bypass amino acid (ACT) during late pregnancy on the production performance of cows pre- and postpartum and their offspring.
Jang-Hoon Jo, Jae-Sung Lee, Jalil Ghassemi Nejad, Won-Seob Kim, Jun-Ok Moon, Hong-Gu Lee   +5 more
doaj   +1 more source

2014 REU Poster: Measuring Tryptophan Metabolism Using Analogs of Tryptophan [PDF]

, 2014
Poster presentation at REU Summer's End Research Symposium, 2014, by REU participant Thierno Diallo, Roxbury Community College - John "Chip" Celenza group, Sanda Zolj lab mentorNSF ...
Diallo, Thierno
core   +4 more sources

Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]

, 2016
Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran, Anderson, Katie, Berryhill, Grace, Chen, Ching-Hsien, Graef, Ashley, Hovey, Russell C, Kim, Jeffrey, Modiano, Jaime F, Sarver, Aaron L, Stewart, Benjamin, Trott, Josephine F, Uzal, Francisco, Weiss, Robert H, Wettersten, Hiromi   +13 more
core   +2 more sources

Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19

Cells, 2021
The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide challenge. The present large study sought to understand independent and overlapping metabolic features of samples from acutely ill patients (n = 831) that tested positive ...
Angelo D’Alessandro, Tiffany Thomas, Imo J. Akpan, Julie A. Reisz, Francesca I. Cendali, Fabia Gamboni, Travis Nemkov, Kiruphagaran Thangaraju, Upendra Katneni, Kenichi Tanaka, Stacie Kahn, Alexander Z. Wei, Jacob E. Valk, Krystalyn E. Hudson, David Roh, Chiara Moriconi, James C. Zimring, Eldad A. Hod, Steven L. Spitalnik, Paul W. Buehler, Richard O. Francis   +20 more
doaj   +1 more source

Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]

, 2018
BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach, Beeken, Bettenworth, Clayton, Coburn, Dąbrowski, Gupta, Hashimoto, Hou, Kim, Kim, Li, Liu, Liu, Middleton, Morgan, Nikolaus, Ren, Richard, Ruth, Schrocksnadel, Tsune, Walser, Wang, Widner, Xin   +25 more
core   +4 more sources

Transport of tryptophan dipeptide derivatives and impact on inflammatory cytokines in monocyte/macrophage-like cells

Heliyon
Background: Tryptophan is an essential amino acid with anti-inflammatory and immunomodulatory effects. However, the absorption of amino acids including tryptophan is relatively slower than the absorption of dipeptides. Therefore, we have two aims in this
Jae B. Park, Renee Peters
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The use of isotopic carbon in a study of the metabolism of anthanilic acid in Neurospora [PDF]

, 1949
The finding by Tatum, Banner, and Beadle (l), that the tryptophanless Neurospora mutant strain 10575 accumulates anthranilic acid, which in turn can be utilized for growth of strain 40008, has provided evidence that anthranilic acid is a biochemical ...
Langham, Wright H., Leifer, Edgar, Mitchell, Herschel K., Nyc, Joseph F.   +3 more
core  

Methane emissions from the 2015 Aliso Canyon blowout in Los Angeles, CA. [PDF]

, 2016
Single-point failures of natural gas infrastructure can hamper methane emission control strategies designed to mitigate climate change. The 23 October 2015 blowout of a well connected to the Aliso Canyon underground storage facility in California ...
Blake, DR, Conley, S, Faloona, I, Franco, G, Peischl, J, Ryerson, TB   +5 more
core   +1 more source