Results 21 to 30 of about 270,080 (298)

Tryptophan Modulatory Role in European Seabass (Dicentrarchus labrax) Immune Response to Acute Inflammation under Stressful Conditions [PDF]

, 2022
The present work aimed to study the role of dietary tryptophan supplementation in modulating the European seabass (Dicentrarchus labrax) immune condition during stressful rearing conditions (i.e., 15 days exposure to high density), as well as the immune ...
Paulo Santos, Marina Machado, Aragão, Cláudia, Carvalho, Inês, Diogo Peixoto, Azeredo, Rita, Raquel Cêa de Aragão Teixeira, Cláudia, Machado, Marina, Inês Duarte, Duarte, Inês, Inês Carvalho, Cláudia Aragão, Peixoto, Diogo, Rita Azeredo, Benjamín Costas, Santos, Paulo, Costas, Benjamín, Ricardo, Ana, Ana Ricardo   +18 more
core   +1 more source

Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle.

PLoS Biology, 2007
Mammalian cells rely on cellular uptake of the essential amino acid tryptophan. Tryptophan sequestration by up-regulation of the key enzyme for tryptophan degradation, indoleamine 2,3-dioxygenase (IDO), e.g., in cancer and inflammation, is thought to ...
Thijs Kaper, Loren L Looger, Hitomi Takanaga, Michael Platten, Lawrence Steinman, Wolf B Frommer   +5 more
doaj   +1 more source

Metabolic and Stress Responses in Senegalese Soles (Solea senegalensis Kaup) Fed Tryptophan Supplements: Effects of Concentration and Feeding Period

Animals, 2019
The objective of this study was to assess the impact of different dietary Trp concentrations on the stress and metabolism response of juvenile Senegalese soles (Solea senegalensis).
Marcelino Herrera, Juan M. Miró, Inmaculada Giráldez, Natalia Salamanca, Juan A. Martos-Sitcha, Juan M. Mancera, Jose R. López   +6 more
doaj   +1 more source

Tryptophan to Tryptophan Hole Hopping in an Azurin Construct

The Journal of Physical Chemistry B, 2023
Electron transfer (ET) between neutral and cationic tryptophan residues in the azurin construct [ReI(H126)(CO)3(dmp)](W124)(W122)CuI (dmp = 4,7-Me2-1,10-phenanthroline) was investigated by Born-Oppenheimer quantum-mechanics/molecular mechanics/molecular dynamics (QM/MM/MD) simulations.
Martin Melčák, Filip Šebesta, Jan Heyda, Harry B. Gray, Stanislav Záliš, Antonín Vlček   +5 more
openaire   +4 more sources

Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism

Frontiers in Immunology, 2022
Ulcerative colitis (UC) is a chronic and recurrent inflammatory disorder in the gastrointestinal tract. Here, we examined the pharmacological effects of ginsenoside Rg1, a natural compound with low bioavailability, on the acute experimental colitis mice ...
Hao Cheng, Juan Liu, Dandan Zhang, Jing Wang, Yuzhu Tan, Yuzhu Tan, Wuwen Feng, Wuwen Feng, Cheng Peng, Cheng Peng   +9 more
doaj   +1 more source

Tryptophan-PNA gc Conjugates Self-Assemble to Form Fibers

, 2023
Peptide nucleic acids and their conjugates to peptides can self-assemble and generate complex architectures. In this work, we explored the self-assembly of PNA dimers conjugated to the dipeptide WW.
Marilisa Leone (1479286), Flavia Anna Mercurio (8631084), Luisa De Cola, Flavia Anna Mercurio, Alessandra Romanelli, Alessandra Romanelli (166215), Andrea Mosseri (16641916), María Sancho-Albero (8804909), Andrea Mosseri, María Sancho-Albero, Luisa De Cola (8148900), Marilisa Leone   +11 more
core   +1 more source

Effects of Dietary Supplementation of Acetate and L-Tryptophan Conjugated Bypass Amino Acid on Productivity of Pre- and Post-Partum Dairy Cows and Their Offspring

Animals, 2021
In this study, we investigated the effect of dietary supplementation with acetate and L-tryptophan-conjugated bypass amino acid (ACT) during late pregnancy on the production performance of cows pre- and postpartum and their offspring.
Jang-Hoon Jo, Jae-Sung Lee, Jalil Ghassemi Nejad, Won-Seob Kim, Jun-Ok Moon, Hong-Gu Lee   +5 more
doaj   +1 more source

Transport of tryptophan dipeptide derivatives and impact on inflammatory cytokines in monocyte/macrophage-like cells

Heliyon
Background: Tryptophan is an essential amino acid with anti-inflammatory and immunomodulatory effects. However, the absorption of amino acids including tryptophan is relatively slower than the absorption of dipeptides. Therefore, we have two aims in this
Jae B. Park, Renee Peters
doaj   +1 more source

Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19

Cells, 2021
The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide challenge. The present large study sought to understand independent and overlapping metabolic features of samples from acutely ill patients (n = 831) that tested positive ...
Angelo D’Alessandro, Tiffany Thomas, Imo J. Akpan, Julie A. Reisz, Francesca I. Cendali, Fabia Gamboni, Travis Nemkov, Kiruphagaran Thangaraju, Upendra Katneni, Kenichi Tanaka, Stacie Kahn, Alexander Z. Wei, Jacob E. Valk, Krystalyn E. Hudson, David Roh, Chiara Moriconi, James C. Zimring, Eldad A. Hod, Steven L. Spitalnik, Paul W. Buehler, Richard O. Francis   +20 more
doaj   +1 more source

Tryptophan transport in human fibroblast cells : a functional characterization

, 2011
There are indications that serotonergic neurotransmission is disturbed in several psychiatric disorders. One explanation may be disturbed transport of tryptophan (precursor for serotonin synthesis) across cell membranes.
Lewander, Tommy, Venizelos, Nikolaos, Lewander, Tommy,, Nikolaos Venizelos, Johansson, Jessica, Johansson, Jessica,, Jessica Johansson, Vumma, Ravi,, Vumma, Ravi, Venizelos, Nikolaos,, Ravi Vumma, Tommy Lewander   +11 more
core   +1 more source