Amino acid metabolism in primary bone sarcomas
Frontiers in Oncology, 2022 Primary bone sarcomas, including osteosarcoma (OS) and Ewing sarcoma (ES), are aggressive tumors with peak incidence in childhood and adolescence. The intense standard treatment for these patients consists of combined surgery and/or radiation and maximal
Jennifer A. Jiménez +6 more
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Amino Acid Metabolism in Cancer Drug Resistance
Cells, 2022 Despite the numerous investigations on resistance mechanisms, drug resistance in cancer therapies still limits favorable outcomes in cancer patients.
Hee-Chan Yoo, Jung-Min Han
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Effects of sex and site on amino acid metabolism enzyme gene expression and activity in rat white adipose tissue [PDF]
, 2016 Podeu consultar dades primàries associades a l'article a: http://hdl.handle.net/2445/66872Background and Objectives.White adipose tissue (WAT) shows marked sex- and diet-dependent differences.However, our metabolic knowledge ofWAT, especially on amino ...
Agnelli, Silvia +4 more
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Amino Acid Metabolism and Disease
International Journal of Molecular Sciences, 2023 The origin of life is still a matter of debate, and several hypotheses have been proposed to explain how the building blocks leading to the minimal cell were formed [...]
openaire +3 more sources
White adipose tissue urea cycle activity is not affected by one-month treatment with a hyperlipidic diet in female rats. [PDF]
, 2016 Under high-energy diets, amino acid N is difficult to dispose of, as a consequence of the availability of alternative substrates. We found, recently, that WAT contains a complete functional urea cycle, we analyzed the possible overall changes in the WAT ...
Agnelli, Silvia +4 more
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Metabolism of amino acid amides in Pseudomonas putida ATCC 12633 [PDF]
, 1993 The metabolism of the natural amino acid L-valine, the unnatural amino acids D-valine, and D-, L-phenylglycine (D-, L-PG), and the unnatural amino acid amides D-, L-phenylglycine amide (D, L-PG-NH2) and L-valine amide (L-Val-NH2) was studied in ...
Croes, L.M., +4 more
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Hypoxic Adaptation of Mitochondrial Metabolism in Rat Cerebellum Decreases in Pregnancy
Cells, 2020 Function of brain amino acids as neurotransmitters or their precursors implies changes in the amino acid levels and/or metabolism in response to physiological and environmental challenges.
Anastasia Graf +4 more
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Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism
eLife, 2021 Interleukin-4-induced-1 (IL4i1) is an amino acid oxidase secreted from immune cells. Recent observations have suggested that IL4i1 is pro-tumorigenic via unknown mechanisms.
Leonie Zeitler +13 more
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Isotopic and genetic methods reveal the role of the gut microbiome in mammalian host essential amino acid metabolism. [PDF]
, 2020 Intestinal microbiota perform many functions for their host, but among the most important is their role in metabolism, especially the conversion of recalcitrant biomass that the host is unable to digest into bioavailable compounds.
Bradley, Christina J +5 more
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Amino acid metabolism conflicts with protein diversity [PDF]
, 2014 The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine.
Alonso, Leonardo G. +6 more
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