Results 11 to 20 of about 683,558 (264)

Identification of an amino acid metabolism-associated gene signature predicting the prognosis and immune therapy response of clear cell renal cell carcinoma

open access: yesFrontiers in Oncology, 2022
BackgroundThe upregulation of amino acid metabolism is an essential form of metabolic reprogramming in cancer. Here, we developed an amino acid metabolism signature to predict prognosis and anti-PD-1 therapy response in clear cell renal cell carcinoma ...
Fan Zhang   +6 more
doaj   +1 more source

Oncology Therapeutics Targeting the Metabolism of Amino Acids

open access: yesCells, 2020
Amino acid metabolism promotes cancer cell proliferation and survival by supporting building block synthesis, producing reducing agents to mitigate oxidative stress, and generating immunosuppressive metabolites for immune evasion.
Nefertiti Muhammad   +2 more
doaj   +1 more source

Research Progress of Amino Acid Metabolism PET Imaging in Tumor

open access: yesJournal of Isotopes, 2015
Amino acid metabolism PET imaging plays a very important role in metabolism molecular imaging. Amino acid PET tracers include [1-11C]amino acid, labeling α-C amino acid, labeling side-chain amino acid, and N-substituted labeling amino acid.
NIE Da-hong, TANG Gang-hua2
doaj   +1 more source

Integrated nontargeted and targeted metabolomics analyses amino acids metabolism in infantile hemangioma

open access: yesFrontiers in Oncology, 2023
Infantile hemangioma (IH) is the most common benign tumor in children. However, the exact pathogenesis of IH remains unclear. Integrated nontargeted and targeted metabolic analyses were performed to obtain insight into the possible pathogenic mechanism ...
Kaiying Yang   +7 more
doaj   +1 more source

Connections Between Amino Acid Metabolisms in Plants: Lysine as an Example

open access: yesFrontiers in Plant Science, 2020
Extensive efforts have been made to fortify essential amino acids and boost nutrition in plants, but unintended effects on growth and physiology are also observed.
Qingqing Yang   +4 more
doaj   +1 more source

Multi-Omics Data Reveal Amino Acids Related Genes in the Common Carp Cyprinus carpio

open access: yesFishes, 2022
Amino acids have important physiological effects on fish growth and development and are essential nutrition for humans. Flavor-related amino acids, such as glutamic acid and glycine, could have a significant effect on the taste of fish flesh.
Hanyuan Zhang   +8 more
doaj   +1 more source

Determination of a steady-state isotope dilution protocol for carbon oxidation studies in the domestic cat

open access: yesJournal of Nutritional Science, 2023
The present study aimed to develop an isotope protocol to achieve equilibrium of 13CO2 in breath of cats during carbon oxidation studies using L-[1-13C]-Phenylalanine (L-[1-13C]-Phe), provided orally in repeated meals.
Julia Guazzelli Pezzali   +3 more
doaj   +1 more source

Amino Acids and Their Metabolism in Atherosclerosis [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2019
As a leading cause of death worldwide, cardiovascular disease is a global health concern. The development and progression of atherosclerosis, which ultimately gives rise to cardiovascular disease, has been causally linked to hypercholesterolemia.
Katrin, Nitz   +2 more
openaire   +2 more sources

Atherosclerosis Linked to Aberrant Amino Acid Metabolism and Immunosuppressive Amino Acid Catabolizing Enzymes

open access: yesFrontiers in Immunology, 2020
Cardiovascular disease is the leading global health concern and responsible for more deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory disease in the arterial wall, which underpins several types of cardiovascular
Bozidarka L. Zaric   +8 more
doaj   +1 more source

Amino Acid Metabolism and Disease

open access: yesInternational Journal of Molecular Sciences, 2023
The origin of life is still a matter of debate, and several hypotheses have been proposed to explain how the building blocks leading to the minimal cell were formed [...]
openaire   +3 more sources

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