Results 51 to 60 of about 1,137,079 (306)

Metabolic and Stress Responses in Senegalese Soles (Solea senegalensis Kaup) Fed Tryptophan Supplements: E ects of Concentration and Feeding Period [PDF]

, 2019
The objective of this study was to assess the impact of di erent dietary Trp concentrations on the stress and metabolism response of juvenile Senegalese soles (Solea senegalensis). Fish (38.1 1.9 g) were fed di erent Trp-enriched feeds (0%, 1% and 2%
Giráldez, Inmaculada, Herrera, Marcelino, López, Jose R., Mancera Romero, Juan Miguel, Martos Sitcha, Juan Antonio, Miró, Juan M., Salamanca, Natalia   +6 more
core   +4 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Transcriptional regulation of amino acid metabolism in response to nitrogen deficiency and nitrogen forms in tea plant root (Camellia sinensis L.)

Scientific Reports, 2020
Free amino acids, including theanine, glutamine and glutamate, contribute greatly to the pleasant taste and multiple health benefits of tea. Amino acids in tea plants are mainly synthesized in roots and transported to new shoots, which are significantly ...
Tianyuan Yang, Huiping Li, Yuling Tai, Chunxia Dong, Xunmin Cheng, Enhua Xia, Ziping Chen, Fang Li, Xiaochun Wan, Zhaoliang Zhang   +9 more
doaj   +1 more source

The effect of amino acid deprivation on the transfer of iron through Caco-2 cell monolayers [PDF]

, 2017
Funding Source Rural and Environmental Scientific and Analytical Services, the Scottish Government Acknowledgments We thank Dr Helen Hayes for her technical support during this project.
Cottin, Sarah, McArdle, Harry J., Roussel, Guenievre, Stevens, Valerie   +3 more
core   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Amino Acid and Fatty Acid Metabolism Disorders Trigger Oxidative Stress and Inflammatory Response in Excessive Dietary Valine-Induced NAFLD of Laying Hens

Frontiers in Nutrition, 2022
Non-alcoholic fatty liver disease (NAFLD) is a chronic and metabolic liver disease and commonly occurs in humans with obesity and type 2 diabetes mellitus (T2DM); such a condition also exists in animals such as rodents and laying hens.
Huafeng Jian, Huafeng Jian, Huafeng Jian, Huafeng Jian, Huafeng Jian, Qianqian Xu, Qianqian Xu, Qianqian Xu, Qianqian Xu, Qianqian Xu, Xiaoming Wang, Xiaoming Wang, Xiaoming Wang, Xiaoming Wang, Xiaoming Wang, Yating Liu, Yating Liu, Yating Liu, Yating Liu, Yating Liu, Sasa Miao, Sasa Miao, Sasa Miao, Sasa Miao, Sasa Miao, Yan Li, Yan Li, Yan Li, Yan Li, Yan Li, Tianming Mou, Tianming Mou, Tianming Mou, Tianming Mou, Tianming Mou, Xinyang Dong, Xinyang Dong, Xinyang Dong, Xinyang Dong, Xinyang Dong, Xiaoting Zou, Xiaoting Zou, Xiaoting Zou, Xiaoting Zou, Xiaoting Zou   +44 more
doaj   +1 more source

Laboratory Generated Artifacts in Plasma Amino acid Quantitation [PDF]

, 2002
The pace of physicians’ involvement in amino acid metabolism has been enormous in the last five decades. With further development of technology to identify and quantitate upto picomoles of amino acids, their metabolites and related peptides, diagnosis ...
Rao Nanjunda, Mr Ananth
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Targeting pivotal amino acids metabolism for treatment of leukemia

Heliyon
Metabolic reprogramming is a crucial characteristic of cancer, allowing cancer cells to acquire metabolic properties that support their survival, immune evasion, and uncontrolled proliferation.
Jiankun Hong, Wuling Liu, Xiao Xiao, Babu Gajendran, Yaacov Ben-David   +4 more
doaj   +1 more source

Regulation of amino acid metabolism in Aphis gossypii parasitized by Binodoxys communis

Frontiers in Nutrition, 2022
The vast majority of parasitoids are capable of precise and meticulous regulation of nutrition and metabolism within the host. An important building block of life, amino acids are critical to the development of parasitoids.
Hui Xue, Hui Xue, Yunyun Zhao, Yunyun Zhao, Li Wang, Li Wang, Xiangzhen Zhu, Xiangzhen Zhu, Kaixin Zhang, Kaixin Zhang, Dongyang Li, Dongyang Li, Jichao Ji, Jichao Ji, Lin Niu, Lin Niu, Jinjie Cui, Jinjie Cui, Junyu Luo, Junyu Luo, Xueke Gao, Xueke Gao   +21 more
doaj   +1 more source